| TDP-43 regulates LC3ylation in neural tissue through ATG4B cryptic splicing inhibition |
2024 |
Torres, P.; Rico Rios, S.; Ceron Codorniu, M.; Santacreu Vilaseca, M.; Seoane Miraz, D.; Jad, Y.; Ayala, V.; Mariño, G.; Beltran, M.; Miralles, M.P.; Andrés Benito, P.; Fernandez Irigoyen, J.; Santama |
Article d'investigació |
| TDP-43 dysfunction leads to bioenergetic failure and lipid metabolic rewiring in human cells |
2024 |
Ceron Codorniu, M.; Torres, P.; Fernandez Bernal, A.; Rico Rios, S.; Serrano, J.C.E.; Miralles, M.P.; Beltran, M.; Garcera, A.; Soler, R.M.; Pamplona, R.; Portero Otín, M. |
Article d'investigació |
| ERK MAPK signaling pathway inhibition as a potential target to prevent autophagy alterations in spinal muscular atrophy motoneurons |
2023 |
Sansa, A.; Miralles, M.P.; Beltran, M.; Celma Nos, F..; Calderó, J.; Garcera, A..; Soler, R.M. |
Article d'investigació |
| Survival motor neuron protein and neurite degeneration are regulated by Gemin3 in spinal muscular atrophy motoneurons |
2022 |
Miralles, M.P.; Sansa, A.; Beltran, M.; Soler, R.M.; Garcera, A. |
Article d'investigació |
| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) |
2021 |
Klionsky, D.; Canti, C.; Garcera, A.; Herreros, J.; Soler, R.M. |
Article d'investigació |
| Spinal Muscular Atrophy autophagy profile is tissue-dependent: differential regulation between muscle and motoneurons |
2021 |
Sansa, A.; Hidalgo, I.; Miralles, M.P.; de la Fuente, S.; Perez Garcia, M.J.; Munell, F.; Soler, R.M.; Garcera, A. |
Article d'investigació |
| Intracellular pathways involved in cell survival are deregulated in mouse and human spinal muscular atrophy motoneurons |
2021 |
Sansa, A.; de la Fuente, S.; Comella, J.X.; Garcera, A.; Soler, R.M. |
Article d'investigació |
| Calpain system is altered in survival motor neuron-reduced cells from in vitro and in vivo spinal muscular atrophy models |
2020 |
de la Fuente, S.; Sansa, A.; Hidalgo, I.; Vivancos, N.; Romero Guevara, R.; Garcera, A.; Soler, R.M. |
Article d'investigació |
| The Y172 monoclonal antibody against p-c-Jun (Ser63) is a marker of the postsynaptic compartement of c-type cholinergic afferent synapses on motoneurons |
2020 |
Gatius, A.; Tarabal, O.; Cayuela, P.; Casanovas, A.; Piedrafita, L.; Salvany, S.; Hernandez, S.; Soler, R.M.; Esquerda, J.E.; Caldero, J. |
Article d'investigació |
| Isolation, establishment and characterization of a primary culture of embryonic mouse motoneurons |
2019 |
Garcera A; Gou-Fabregas M; Soler RM |
Capítol de llibre d'investigació |
| Sp1-regulated expression of p11 contributes to motor neuron degeneration by membrane insertion of TASK1 |
2019 |
García Morales, V.; Rodríguez Bey, G.; Gómez Pérez, L.; Domínguez Vías, G.; González Forero, D.; Portillo, F.; Campos Caro, A.; Gento Caro, A.; Issaoui, N.; Soler, R.M.; Garcerá, A.; Moreno Lopez, B. |
Article d'investigació |
| Calpain inhibition increases SMN protein in spinal cord motoneurons and ameliorates the spinal muscular atrophy phenotype |
2019 |
de la Fuente, S.; Sansa, A.; Periyakaruppiah, A.; Garcera, A.; Soler, R.M. |
Article d'investigació |
| Evolución previsible en el número de profesores permanentes de Medicina del 2017 al 2026. La formación de los futuros médicos en situación crítica. |
2018 |
JP Lara; Conferencia de Decanos de Fcultades de Medicina de España |
Article docent |
| Regulation of survival motor neuron protein by the nuclear factor-kappa B pathway in mouse spinal cord motoneurons |
2018 |
Arumugam, S.; Mincheva Tasheva, S.; Periyakaruppiah, A.; de la Fuente, S.; Soler, R.M.; Garcera, A. |
Article d'investigació |
| Inhibition of autophagy delays motoneuron degeneration and extends lifespan in a mouse model of spinal muscular atrophy |
2017 |
Piras A, Schiaffino L, Boido M, Valsecchi V, Guglielmotto M, De Amicis E, Puyal J, Garcera A, Tamagno E, Soler RM, Vercelli A. |
Article d'investigació |
| Smn-deficiency increases the intrinsic excitability of motoneurons |
2017 |
Arumugam S; Garcera A; Soler RM; Tabares L |
Article d'investigació |
| Autophagy modulators regulate survival motor neuron protein stability in motoneurons |
2016 |
Periyakaruppiah A, de la Fuente S, Arumugam S, Bahí B, Garcera A, Soler RM. |
Article d'investigació |
| Calpain activation and CaMKIV reduction in spinal cords from hSODG93A mouse model |
2014 |
Gou-Fabregas M; Ramirez-Nuñez O; Cacabelos D; Bahi N; Portero M; Garcera A; Soler RM |
Article d'investigació |
| Survival motor neuron protein reduction deregulates autophagy in spinal cord motoneurons in vitro |
2013 |
Garcera A, Bahi N, Periyakaruppiah A, Arumugam S, Soler RM. |
Article d'investigació |
| NF-kappa B Signaling Pathways: Role in Nervous System Physiology and Pathology |
2013 |
Mincheva-Tasheva S, Soler RM. |
Article d'investigació |
| Notch Signaling Pathway Is Activated in Motoneurons of Spinal Muscular Atrophy |
2013 |
Caraballo-Miralles V, Cardona-Rossinyol A, Garcera A, Torres-Benito L, Soler RM, Tabares L, Lladó J, Olmos G. |
Article d'investigació |
| SMN deficiency attenuates migration of U87MG astroglioma cells through the activation of RhoA |
2012 |
Caraballo-Miralles V, Cardona-Rossinyol A, Garcera A, Villalonga P, Soler RM, Olmos G, Lladó J. |
Article d'investigació |
| A new model to study spinal muscular atrophy: neurite degeneration and cell death is counteracted by Bcl-xL overexpression in motoneurons |
2011 |
Garcera A, Mincheva S, Gou-Fabregas M, Caraballo-Miralles V, Lladó J, Comella JX, Soler RM. |
Article d'investigació |
| The canonical nuclear factor-kappaB Pathway regulates cell survival in a developmental model of spinal cord motoneurons |
2011 |
Mincheva, S.; Garcera, A.; Gou Fabregas, M.; Encinas, M.; Dolcet, X.; Soler, R.M. |
Article d'investigació |
| Estrategias neuroprotectoras que implican a los factores neurotróficos, sus receptores y los mecanismos de señalización intracelular |
2010 |
RM Soler |
Capítol de llibre docent |
| The death receptor antagonist FLIP-L interacts with Trk and is necessary for neurite outgrowth induced by neurotrophins |
2010 |
Moubarak RS, Solé C, Pascual M, Gutierrez H, Llovera M, Pérez-García MJ, Gozzelino R, Segura MF, Iglesias-Guimarais V, Reix S, Soler RM, Davies AM, Soriano E, Yuste VJ, Comella JX. |
Article d'investigació |
| Specific vulnerability of mouse spinal cord motoneurons to membrane depolarization |
2009 |
Gou-Fabregas M, Garcera A, Mincheva S, Perez-Garcia MJ, Comella JX, Soler RM. |
Article d'investigació |
| Tumor necrosis factor alpha and interferon gamma cooperatively induce oxidative stress and motoneuron death in rat spinal cord embryonic explants |
2009 |
Mir M, Asensio VJ, Tolosa L, Gou-Fabregas M, Soler RM, Lladó J, Olmos G. |
Article d'investigació |
| Neuroprotection by neurotrophic factors and membrane depolarization is regulated by calmodulin kinase IV |
2008 |
Pérez-García MJ, Gou-Fabregas M, de Pablo Y, Llovera M, Comella JX, Soler RM. |
Article d'investigació |
| Tyr-701 is a new regulatory site for neurotrophin receptor TrkA trafficking and function |
2008 |
de Pablo Y, Pérez-García MJ , Georgieva MV, Sanchis D, Lindqvist N, Soler RM, Comella JX, Llovera M. |
Article d'investigació |
| Pyruvate protects cerebellar granular cells from 6-hydroxydopamine-induced cytotoxicity by activating the Akt signaling pathway and increasing glutathione peroxidase expression. |
2006 |
Fernandez-Gomez FJ, Pastor MD, Garcia-Martinez EM, Melero-Fernandez de Mera R, Gou-Fabregas M, Gomez-Lazaro M, Calvo S, Soler RM, Galindo MF, Jordan J. |
Article d'investigació |
| Glial cell line-derived neurotrophic factor increases intracellular calcium concentration: role of calcium/calmodulin in the activation of the phosphatidyl inositol 3-kinase pathway |
2004 |
Pérez-García MJ, Ceña V, de Pablo Y, Llovera M, Comella JX, Soler RM. |
Article d'investigació |
| Cytokines promote motoneuron survival through the Janus kinase-dependent activation of the phosphatidylinositol 3-kinase pathway |
2001 |
Dolcet X, Soler RM, Gould TW, Egea J, Oppenheim RW, Comella JX. |
Article d'investigació |
| Neuronal survival induced by neurotrophins requires calmodulin |
2001 |
Egea, J.; Espinet, C.; Soler, R.M.; Dolcet, X.; Yuste, V.J.; Encinas, M.; Iglesias, M.; Rocamora, N.; Comella, J.X. |
Article d'investigació |
| Ca2+ and calmodulin regulate neuronal survival trought the modulation of the intracellular signaling pathways activated by receptors for neurotrophic factors |
2000 |
Comella JX, Egea J, Soler RM, Dolcet X, Espinet C. |
Article d'investigació |
| Nerve growth factor activation of the extracellular signal-regulated kinase pathway is modulated by Ca2+ and calmodulin |
2000 |
Egea J, Espinet C, Soler RM, Peiro S, Rocamora N, Comella JX. |
Article d'investigació |
| Activation of phosphatidylinositol 3-kinase, but not extracellular-regulated kinases, is necessary to mediate brain-derived neurotrophic factor-induced motoneuron survival |
1999 |
Dolcet X*, Egea J*, Soler R, Martin-Zanca D, Comella JX. |
Article d'investigació |
| Receptors of the glial cell line-derived neurotrophic factor family of neurotrophic factors signal cell survival through the phosphatidylinositol 3-kinase pathway in spinal cord motoneurons |
1999 |
Soler, R.M.; Dolcet, X.; Encinas, M.; Egea, J.; Bayascas, J.R.; Comella, J.X. |
Article d'investigació |
| Development of survival responsiveness to BDNF, NT3, NT4/5, but not to NGF, in cultured motoneurons from chick embryo spinal cord |
1998 |
Becker E, Soler RM, Yuste VJ, Giné E, Sanz-Rodriguez C, Egea J, Martin-Zanca D, Comella JX. |
Article d'investigació |
| Point mutation in trkB causes loss of NT4-dependent neurons without major effects on diverse BDNF responses |
1998 |
Minichiello L, Casagranda F, Soler Tatché R, Stucky CL, Postigo A, Lewin GR, Davies AM, Klein R. |
Article d'investigació |
| Calmodulin Is Involved in Membrane Depolarization-Mediated Survival of Motoneurons by Phosphatidylinositol-3 Kinase- and MAPK-Independent Pathways |
1998 |
Soler RM, Egea J, Mintenig GM, Sanz C, Iglesias M, Comella JX. |
Article d'investigació |
| Apoptosis y cáncer. |
1996 |
Comella, J.X.; Boix, J.; Soler, R.M.; Iglesias, M.; Llecha, N.; Egea, J. |
Capítol de llibre d'investigació |
| The carbohydrate N-acetylglucosamine is involved in the guidance of neurites from chick ciliary ganglion neurons through the extracellular matrix of rat skeletal muscle fiber |
1996 |
Iglesias M, Soler RM, Ribera J, Esquerda JE, Comella JX. |
Article d'investigació |
| S-laminin and N-acetylgalactosamine located at the synaptic basal lamina of skeletal muscle are involved in synaptic recognition by growing neurites |
1995 |
Iglesias M, Soler RM, Hunter DD, Ribera J, Esquerda JE, Comella JX. |
Article d'investigació |
| Cultivo de neuronas colinérgicas y su aplicación al estudio de las interacciones tróficas en el sistema neuromuscular. |
1995 |
Comella JX, Soler RM, Iglesias M, Sanz-Rodriguez C, Esquerda JE |
Capítol de llibre d'investigació |
| Clinical status of motoneuron disease does not correlate with serum neurotoxicity on cultured neurons |
1992 |
Martí-Fábregues J, Soler RM, Esquerda J, Grau JM, Pradas J, Illa I. |
Article d'investigació |
