Master's degree in Biomedical Research

AYALA JOVE, MARIA VICTORIA

Category: SENIOR LECTURER
Academic profile: Doctorate
Department: EXPERIMENTAL MEDICINE
Email: victoria.ayala@udl.cat

Teaching

Teaching Course Subject
Master's Degree in Biomedical Research 1 OXIDATIVE STRESS AND ANTIOXIDANTS
Grau en Infermeria 1 BIOLOGICAL BASIS FOR THE ATTENTION TO THE PERSON: ANATOMY
Grau en Infermeria 1 BIOLOGICAL BASIS FOR THE ATTENTION TO THE PERSON: PHYSIOLOGY
Degree in Nursing 1 BIOLOGICAL BASIS FOR THE ATTENTION TO THE PERSON: ANATOMY
Degree in Nursing 1 BIOLOGICAL BASIS FOR THE ATTENTION TO THE PERSON: PHYSIOLOGY
Degree in Medicine 4 NEUROSCIENCE
Degree in Medicine 6 BACHELOR'S THESIS

Research

Research profile: Fisiopatologia Metabòlica
Thesis Year Direction
Regulació de l'expressió de c-Jun durante el desenvolupament de les motoneurones espinals 2001 Esquerda Colell, Josep; Ribera Calvet, Joan
Publications Year Authors Type
Gender-specific beneficial effects of docosahexaenoic acid dietary supplementation in G93A-SOD1 amyotrophic lateral sclerosis mice 2020 Torres P; Cacabelos D; Pairada J; Bauer KC; Boada J; Fontdevila L; Rossi C; Povedano M; Ferrer I; Pamplona R; Finlay BB; Portero-Otín M; Ayala V Article d'investigació
Effects of aging and methionine restriction on rat kidney metabolome. 2019 Pradas I; Jove M; Cabre R; Ayala V; Mota-Martorell N; Pamplona R. Article d'investigació
Cryptic exon splicing function of TARDBP interacts with autophagy in nervous tissue. 2018 Torres, P.; Ramírez-Núñez, O.; Romero-Guevara, R.; Barés, G.; Granado-Serrano, A.B.; Ayala, V.; Boada, J.; Fontdevila, L.; Povedano, M.; Sanchís, D.; Pamplona, R.; Ferrer, I.; Portero-Otín, M. Article d'investigació
Lipidomics Reveals a Tissue-Specific Fingerprint 2018 Pradas I; Huynh K; Cabré R; Ayala V; Meikle PJ; Jové M; Pamplona R. Article d'investigació
Lipid profile in human frontal cortex is sustained throughout healthy adult lifespan to decay at advanced ages 2018 Cabré R; Naudí A; Dominguez-Gonzalez M; Jové M; Ayala V; Mota-Martorell N; Pradas I; Nogueras L; Rué M; Portero-Otín M; Ferrer I; Pamplona R Article d'investigació
Membrane lipid unsaturation as physiological adaption to animal longevity. 2017 Naudí A, Jové M, Ayala V, Portero-Otin M, Barja G, Pamplona R. Capítol de llibre docent
Specific metabolomics adaptations define a differential regional vulnerability in the human cerebral cortex. 2017 Cabré R; Jové M; Naudí A; Ayala V; Piñol-Ripoll G; Gil-Villar MP; Dominguez-Gonzalez M; Obis E; Berdun R; Mota-Martorell N; Portero-Otin M; Ferrer I: Pamplona R. Capítol de llibre docent
Region-specific vulnerability to lipid peroxidation and evidence of neuronal mechanisms for polyunsaturated fatty acid biosynthesis in the healthy adult human central nervous system 2017 Naudí A, Cabré R, Dominguez-Gonzalez M, Ayala V, Jové M, Mota-Martorell N, Piñol-Ripoll G, Gil-Villar MP, Rué M, Portero-Otín M, Ferrer I, Pamplona R. Article d'investigació
Sixty years-old is the breakpoint of the human frontal cortex aging. 2017 Cabré R; Naudí A; Dominguez-Gonzalez M; Ayala V; Jové M; Mota-Martorell N; Piñol-Ripoll G;Gil-Villar MP; Rué M; Portero-Otín M; Ferrer I; Pamplona R Article d'investigació
Early and gender-specific differences in spinal cord mitochondrial function and oxidative stress markers in a mouse model of ALS 2016 Cacabelos D; Ramírez-Núñez O; Granado-Serrano AB; Torres P; Ayala V; Moiseeva V; Povedano M; Ferrer I; Pamplona R; Portero-Otin M; Boada J. Article d'investigació
Specific metabolomics adaptations define a differential regional vulnerability in the adult human cerebral cortex 2016 Cabré R; Jové M; Naudí A; Ayala V; Piñol-Ripoll G; Gil-Villar MP; Dominguez-Gonzalez M; Obis E; Berdun R; Mota-Martorell N; Portero-Otin M; Ferrer I; Pamplona R. Article d'investigació
Interplay between TDP-43 and docosahexaenoic acid-related processes in amyotrophic lateral sclerosis 2016 Cacabelos D; Ayala V; Granado-Serrano AB; Jové M; Torres P; Boada J; Cabré R; Ramírez-Núñez O; Gonzalo H; Soler-Cantero A; Serrano JC; Bellmunt MJ, Romero MP; Motilva MJ; Nonaka T; Hasegawa M; Ferrer Article d'investigació
Do primary health centres and hospitals contribute equally towards achievement of the transversal clinical competencies of medical students? Performance on the Objective Structured Clinical Examinatio 2015 Soler-González J; Buti M; Boada J; Ayala V; Peñascal E; Rodriguez T; GERDS group. Article en premsa
Lipidomics of Human Brain Aging and Alzheimer's Disease Pathology 2015 Naudí A, Cabré R, Jové M, Ayala V, Gonzalo H, Portero-Otín M, Ferrer I, Pamplona R. Review
Target of rapamycin activation predicts lifespan in fruit flies 2015 Scialo F, Sriram A, Naudí A, Ayala V, Jové M, Pamplona R, Sanz A. Article d'investigació
Dietary Lipid Unsaturation Influences Survival and Oxidative Modifications of an Amyotrophic Lateral Sclerosis Model in a Gender-Specific Manner 2014 Cacabelos D, Ayala V, Ramirez-Nuñez O, Granado-Serrano AB, Boada J, Serrano JCE, Cabre R, Nadal-Rey G, Bellmunt MJ, Ferrer I, Pamplona R, Portero-Otin M. Article d'investigació
Estrés oxidativo, vulnerabilidad neuronal selectiva, y enfermedades neurodegenerativas asociadas a la edad. 2013 Naudi A; Jove M; Ayala V; Cacabelos D; Ramírez O; Ferrer I; Portero-Otin M; Pamplona R. Capítol de llibre docent
Non-enzymatic modification of aminophospholipids by carbonyl-amine reactions 2013 Naudi A, Jove M, Ayala V, Cabre R, Portero-Otin M, Pamplona R. Review
Membrane lipid unsaturation as physiological adaptation to animal longevity 2013 Naudi A; Jove M; Ayala V; Portero-Otin M; Barja G; Pamplona R Article d'investigació
A study of selective neuronal vulnerability in the human central nervous system 2013 Naudí A; Jové M; Ayala V; Cabré R; Portero-Otin M; Ferrer I; Pamplona R. Article d'investigació
Lipidomic and metabolomic analyses reveal potential plasma biomarkers of early atheromatous plaque formation in hamsters 2013 Jove M, Ayala V, Ramirez-Nuñez O, Serrano JCE, Cassanye A, Arola L, Caimari A, del Bas JM, Crescenti A, Pamplona R, Portero-Otin M. Article d'investigació
Skeletal muscle uncoupling-induced longevity in mice is linked to increased substrate metabolism and induction of the endogenous antioxidant defense system. 2013 Keipert S; Ost M; Chadt A; Voigt A; Ayala V; Portero-Otin M; Pamplona R; Al-Hasani H; Klaus S. Article d'investigació
Estudio de la vulnerabilidad neuronal selectiva en el sistema nervioso central humano. 2013 Naudi A; Jove M; Ayala V; Cabre R; Portero-Otin M; Ferrer I; Pamplona R. Article d'investigació
Plasma long-chain free fatty acids predict mammalian longevity 2013 Jove M, Naudi A, Aledo JC, Cabre R, Ayala V, Portero-Otin M, Barja G, Pamplona R. Article d'investigació
Specific Lipidome Signatures in Central Nervous System from Methionine-Restricted Mice 2013 Jové M, Ayala V, Ramírez-Núñez O, Naudí A, Cabré R, Spickett CM, Portero-Otín M, Pamplona R. Article d'investigació
Formation of S-(Carboxymethyl)-cysteine in rat liver mitochondrial proteins. Effects of caloric and methionine restriction. 2013 Naudí A, Jové M, Cacabelos D, Ayala V, Cabré R, Caro P; Gómez J, Portero-Otín M, Barja G, Pamplona R Article d'investigació
Cellular dysfunction in diabetes as maladaptive response to mitochondrial oxidative stress 2012 Naudí A, Jové M, Ayala V, Cassanye A, Serrano J, Gonzalo H, Boada J, Prat J,Portero-Otín M,Pamplona R Review
DJ-1β regulates oxidative stress, insulin-like signaling and development in Drosophila melanogaster. 2012 Stefanatos R; Sriram A; Kiviranta E; Mohan A; Ayala V; Jacobs HT; Pamplona R; Sanz A. Article d'investigació
Region specific vulnerability to lipid peroxidation in the human central nervous system. 2012 Naudi A; Jove M; Ayala V; Ramirez O; Cabre R; Prat J; Portero-Otin M; Ferrer I; Pamplona R. Capítol de llibre docent
Metabolómica Multicompartimental para el Estudio de los Efectos Fisiológicos de Compuestos Activos en Modelos in vivo 2012 Mariona Jové; José CE Serrano; Victòria Ayala; Neus Anglès; Jordi Reguant; José R Morelló; Núria Brunet; Reinald Pamplona; Manuel Portero-Otín Article en premsa
Region specific vulnerability to lipid peroxidation in the human central nervous system. 2012 Alba Naudí; Mariona Jové; Victòria Ayala; Omar Ramírez; Rosanna Cabré; Joan Prat; Manuel Portero-Otín; Isidre Ferrer; Reinald Pamplona. Capítol de llibre docent
Resistencia a la insulina: ¿factor de riesgo o adaptación fisiológica?. 2011 Pamplona R; Serrano J; Boada J; Ayala V; Bellmunt MJ; Espinel A; Delgado MA; Portero-Otin M. Capítol de llibre docent
Cell stress induces TDP-43 pathological changes associated with ERK1/2 dysfunction: implications in ALS 2011 Ayala V, Granado-Serrano AB, Cacabelos D, Naudí A, Ilieva EV, Boada J, Caraballo-Miralles V, Lladó J, Ferrer I, Pamplona R, Portero-Otin M. Article d'investigació
Multicompartmental LC-Q-TOF-Based Metabonomics as an exploratory tool to identify novel pathways affected by polyphenol-rich diets in mice. 2011 Jove, M; Serrano, JCE; Ortega, N; Ayala, V; Angles, N; Reguant, J ; Morello, JR; Romero, MP ; Motilva, MJ; Prat, J ; Pamplona, R ; Portero-Otin, M Article d'investigació
Resistencia a la insulina, ¿Factor de riesgo o adaptación fisiológica? 2011 Reinald Pamplona Gras, José Serrano Casasola, Jordi Boada Pallàs, Victoria Ayala Jove, Maria José Bellmunt Curcó, Manuel Portero-Otin, Alberto Espinel González, Marco Antonio Delgado Capítol de llibre d'investigació
Membrane unsaturation, selective neuronal vulnerability, and age-related neurodegenerative diseases. 2011 Naudi A; Jove M; Cacabelos D; Ramirez O; Ayala V; Ilieva EV; Kichev A; Ferrer I; Portero-Otin M; Pamplona R. Capítol de llibre d'investigació
Forty percent methionine restriction lowers DNA methylation, complex I ROS generation, and oxidative damage to mtDNA and mitochondrial proteins in rat heart. 2011 Sanchez-Roman I; Gomez A; Gomez J; Suarez H; Sanchez C; Naudi A; Ayala V; Portero-Otin M; Lopez-Torres M; Pamplona R; Barja G. Article d'investigació
Endogenous toxins associated with life expectancy and aging 2010 Ayala V, Boada J, Serrano J, Portero-Otin M, Pamplona R Capítol de llibre docent
Pathological aspects of lipid peroxidation 2010 Negre-Salvayre A; Auge N; Ayala V; Basaga H; Boada J; Brenke R; Chapple S; Cohen G; Feher J; Grune T; Lengyel G; Mann GE; Pamplona R; Poli G; Portero-Otin M; Riahi Y; Salvayre R; Sasson S; Serrano J; Article d'investigació
Protein oxidative damage in diabetes. 2010 Reinald Pamplona; Victoria Ayala; Jordi Boada; Jose Serrano; Manuel Portero-Otín. Capítol de llibre d'investigació
Glycation of mitochondrial proteins, oxidative stress and aging 2010 Naudí A, Jové M, Ayala V, Portero-Otín M, Pamplona R Article d'investigació
Lithium prevents excitotoxic cell death of motoneurons in organotypic slice cultures of spinal cord 2010 Calderó, J.; Brunet, N.; Tarabal, O.; Piedrafita, L.; Hereu, M.; Ayala, V.; Esquerda, J.E. Article d'investigació
The beta-blocker atenolol lowers the longevity-related degree of fatty acid unsaturation, decreases protein oxidative damage and increases ERK signaling in heart of C57BL/6 mice. 2010 Sanchez-Roman I, Gomez J, Naudi A, Ayala V, Portero-Otin M, Lopez-Torres M, Pamplona R, Barja G. Article d'investigació
Oxidación de Macromoléculas, Envejecimiento y Longevidad 2009 Naudí A,Jové M,Ilieva E, Cacabelos D, Gonzalo H, Serrano J,Boada J, Ayala V, Portero-Otín M, Pamplona R. Capítol de llibre docent
Forty percent methionine restriction decreases mitochondrial oxygen radical production and leak at complex I during forward electron flow and lowers oxidative damage to proteins and mitochondrial DNA 2009 Caro P, Gomez J, Sanchez I, Naudi A, Ayala V, Lopez-Torres M, Pamplona R, Barja G. Article d'investigació
Bases biológicas del proceso de envejecimiento y la longevidad 2009 Naudí A,Caro P, Barja G, Pamplona R Capítol de llibre docent
Estrés Oxidativo y Lípidos: determinación del índice de peroxidabilidad de los lípidos de membrana y la lesión lipoxidativa a proteínas. 2009 Naudí A,Jové M, Cacabelos D,Ilieva E, Gonzalo H, Serrano J, Ayala V, Boada J, Portero-Otín M, Pamplona R. Capítol de llibre docent
Maillard reaction versus other nonenzymatic modifications in neurodegenerative processes 2008 Pamplona R, Ilieva E, Ayala V, Bellmunt MJ, Cacabelos D, Dalfo E, Ferrer I, Portero-Otin M Article d'investigació
Oxidative and endoplasmic reticulum stress interplay in sporadic amyotrophic lateral sclerosis 2007 Ilieva EV, Ayala V, Jove M, Dalfo E, Cacabelos D, Povedano M, Bellmunt MJ, Ferrer I, Pamplona R, Portero-Otin M. Article d'investigació
Methionine restriction decreases endogenous oxidative molecular damage and increases mitochondrial biogenesis and uncoupling protein 4 in rat brain 2007 Naudi A, Caro P, Jove M, Gomez J, Boada J, Ayala V, Portero-Otin M, Barja G, Pamplona R Article d'investigació
Methylglyoxal induces advanced glycation endproduct (AGEs) formation and dysfunction of PDGF receptor-beta. Implications for diabetic atherosclerosis 2007 Cantero AV, Portero-Otin M, Sanson M, Ayala V, Auge N, Elbaz M, Thiers JC, Pamplona R, Salvayre R, Negre-Salvayre A Article d'investigació
Dietary protein restriction decreases oxidative protein damage, peroxidizability index, and mitochondrial complex I content in rat liver 2007 Ayala V, Naudí A, Sanz A, Caro P, Portero-Otin M, Barja G, Pamplona R. Article d'investigació
The biological basis of the aging process 2007 Naudi A, Jove M, Cacabelos D, Ilieva E, Boada J, Ayala V, Portero-Otin M, Pamplona R Review
Lesion oxidativa de proteinas de higado y corazon de rata durante el proceso de envejecimiento. 2006 Ayala V, Vasileva E, Fernandez E, Modol MT, Bellmunt MJ, Prat J, Requena JR, Portero-Otin M, Pamplona R. Article d'investigació
Differential effect of experimental and cold-induced hyperthyoridism on factors inducing rat liver oxidative damage. 2006 Venditti P, Pamplona R, Ayala V, De Rosa R, Caldarone G, DiMeo S. Article d'investigació
Methionine restriction decreases mitochondrial oxygen radical generation and leak and oxidative damage to mitochondrial DNA and proteins. 2006 Sanz A, Caro P, Ayala V, Portero-Otin M, Pamplona R and Barja G. Article d'investigació
Glial fibrillary acidic protein is a major target of glycoxidative and lipoxidative damage in Pick's disease 2006 Muntane G, Dalfo E, Martinez A, Rey MJ, Avila J, Perez M, Portero M, Pamplona R, Ayala V, Ferrer I. Article d'investigació
Protein and lipid oxidative damage and complex I content are lower in the brain of budgerigar and canaries than in mice. Relation to aging rate. 2005 Pamplona R, Portero-Otin M, Sanz A, Ayala V, Vasileva E, Barja G. Article d'investigació
Evidence of oxidative stress in the neocortex in incidental Lewy body disease. 2005 Dalfo E, Portero-Otin M, Ayala MV, Martinez A, Pamplona R, Ferrer I. Article d'investigació
Proteins in human brain cortex are modified by oxidation, glycoxidation and lipoxidation: effects of Alzheimer's disease and identification of lipoxidation targets. 2005 Pamplona R, Dalfo E, Ayala MV, Bellmunt MJ, Prat J, Ferrer I, Portero-Otin M. Article d'investigació
Protein methionine content and MDA-lysine adducts are inversely related to maximum life span in the heart of mammals 2005 Ruiz MC, Ayala V, Portero-Otin M, Requena JR, Barja G, Pamplona R. Article d'investigació
Protein nonenzymatic modifications and proteasome activity in skeletal muscle from the short-lived rat and long-lived pigeon. 2004 Portero-Otin M, Requena JR, Bellmunt MJ, Ayala V, Pamplona R. Article d'investigació
Rescue of developing spinal motoneurons from programmed cell death by GABAA agonist muscimol acts by blockade of neuromuscular activity and increased intramuscular nerve branching 2003 Oppenheim RW., Calderó J, Ciutat D, Esquerda JE, Ayala V, Prevette D, Wang S. Article d'investigació
c-Jun-like immunoreactivity in apoptosis is the result of a crossreaction with neoantigenic sites exposed by caspase-3-mediated proteolysis. 2002 Ribera J, Ayala V, Esquerda JE. Article d'investigació
Specific association of c-Jun.like immunoreactivity but not c-Jun p39 with normal and induced programmed cell death in the chick embryo 1999 Ayala V, Casas C,Ribera J, Calderó J, Oppenheim RW, Esquerda JE. Article d'investigació