Master's degree in Biomedical Research

PAMPLONA GRAS, REINALDO RAMON

Category: PROFESSOR
Academic profile: Doctorate
Department: EXPERIMENTAL MEDICINE
Email: reinald.pamplona@udl.cat

Teaching

Teaching Course Subject
Master's Degree in Biomedical Research 1 OXIDATIVE STRESS AND ANTIOXIDANTS
Degree in Biomedical Sciences 1 HUMAN PHYSIOLOGY
Degree in Biomedical Sciences 3 CANCER I
Degree in Biomedical Sciences 4 AGEING
Degree in Biomedical Sciences 4 BACHELOR'S THESIS
Degree in Biomedical Sciences 4 PRACTICAL PROJECT
Degree in Medicine 6 BACHELOR'S THESIS

Research

Research profile: Fisiopatologia Metabòlica
Thesis Year Direction
Estado redox periférico y biomarcadores pronóstico en la esclerosis múltiple 2020 Reinald Pamplona Gras
Effect of aging and Methionine restriction on rat tissue metabolomic profiles 2018 Pamplona, Reinald; Jové, Mariona
Implicación de nucleoporinas y su relación con alteraciones de proteóstasis de TDP-43 secundarias a estrés celular en la fisiopatología de la ELA 2017 Manuel Portero; Reinald Pamplona
Tractament dietètic de la resistència a la insulina amb compostos bioactius i els seus efectes en el mitocondri 2014 Jose Serrano i Reinald Pamplona
Polyunsaturated fatty acids in amyotrophic lateral sclerosis. Role of DHA, peroxidative modifications and sexual dimorphism 2014 Manuel Portero; Reinald Pamplona
Pharmacological blockage of voltage-gated calcium channels as a potential cardioprotective strategy. 2014 Carles Canti i Reinald Pamplona
Exercici físic aeròbic en intervals versus continu: una perspectiva fisiològica de la resposta a l’estrès 2012 Reinald Pamplona; Manuel Portero-Otin
Noves eines per a la caracterització d'efectes funcionals de derivats vegetals sobre mecanismes bàsics de l'envelliment i patologies associades 2010 Reinald Pamplona i Manel Portero
Mecanismes d'acció de diferents tipus d'intervencions nutricionals sobre l'estrès oxidatiu i les seves implicacions en el procés fisiològic de l'envelliment 2010 Reinald Pamplona; Manel Portero Otín
Molecular Mechanisms of ageing in neurodegeneration: role of oxidative and endoplasmic reticulum stress in different human diseases 2009 Portero-Otin, Manel; Pamplona Gras, Reinald
Publications Year Authors Type
Lipoxidation: features, neurological tissues, and aging 2021 Pamplona R; Jove M; Pradas I; Mota-Martorell N; Ferrer I. Capítol de llibre docent
Lifelong soya consumption in males does not increase lifespan but increases health span under a metabolic stress such as type 2 diabetes mellitus 2021 Borrás, C.; Abdelaziz, K.M.; Díaz, A.; Gambini, J.; Jové, M.; López Grueso, R.; Mas Bargues, C.; Monleón, D.; Pamplona, R.; Viña, J. Article d'investigació
Dysregulated protein phosphorylation: A determining condition in the continuum of brain aging and Alzheimer's disease 2021 Ferrer, I.; Andrés Benito, P.; Ausín, K.; Pamplona, R.; Del Rio, J.A.; Fernández Irigoyen, J.; Santamaría, E. Article d'investigació
Up-Regulation of Specific Bioactive Lipids in Celiac Disease 2021 Martín Masot, R.; Galo Licona, J.D.; Mota Martorell, N.; Sol, J.; Jové, M.; Maldonado, J.; Pamplona, R.; Nestares, T. Article d'investigació
mTORC1 is also involved in longevity between species 2021 Barja, G.; Pamplona, R. Article d'investigació
Plasma methionine metabolic profile is associated with longevity in mammals 2021 Mota Martorell, N.; Jové, M.; Berdún, R.; Pamplona, R. Article d'investigació
Prevalence and Predictors of Cerebral Microangiopathy Determined by Pulsatility Index in an Asymptomatic Population From the ILERVAS Project 2021 Purroy, F.; Sánchez, E.; Lecube, A.; Arqué, G.; Vicente Pascual, M.; Mauri Capdevila, G.; Torreguitart, N.; Hernández, M.; Barbé, F.; Fernández, E.; Pamplona, R.; Farràs, C.; Mauricio, D.; Bermúdez Ló Article d'investigació
Nuclear lipidome is altered in amyotrophic lateral sclerosis: A pilot study 2021 Ramírez Nuñez, O.; Jové, M.; Torres, P.; Sol, J.; Fontdevila, L.; Romero Guevara, R.; Andrés Benito, P.; Ayala, V.; Rossi, C.; Boada, J.; Povedano, M.; Ferrer, I.; Pamplona, R.; Portero Otin, M. Article d'investigació
The Causal Role of Lipoxidative Damage in Mitochondrial Bioenergetic Dysfunction Linked to Alzheimer's Disease Pathology 2021 Jové, M.; Mota Martorell, N.; Torres, P.; Ayala, V.; Portero Otin, M.; Ferrer, I.; Pamplona, R. Review
Subjects with detectable Saccharomyces cerevisiae in the gut microbiota show deficits in attention and executive function 2021 Arnoriaga Rodríguez, M.; Mayneris Perxachs, J.; Coll, C.; Pérez Brocal, V.; Ricart, W.; Moya, A.; Ramió Torrentà, L.; Pamplona, R.; Jové, M.; Portero Otin, M.; Fernández Real, J.M. Article d'investigació
New insights into human prefrontal cortex aging with a lipidomics approach 2021 Jové, M.; Mota Martorell, N.; Torres, P.; Portero Otin, M.; Ferrer, I.; Pamplona, R. Article d'investigació
Lipidomic traits of plasma and cerebrospinal fluid in amyotrophic lateral sclerosis correlate with disease progression 2021 Sol, J.; Jové, M.; Povedano, M.; Sproviero, W.; Domínguez, R.; Piñol Ripoll, G.; Romero Guevara, R.; Hye, A.; Al Chalabi, A.; Torres, P.; Andres Benito, P.; Area Gómez, E.; Pamplona, R.; Ferrer, I.; A Article d'investigació
Cell Stress Induces Mislocalization of Transcription Factors with Mitochondrial Enrichment 2021 Rossi, C.; Fernàndez, A.; Torres, P.; Ramirez Nuñez, O.; Granado Serrano, A.B.; Fontdevila, L.; Povedano, M.; Pamplona, R.; Ferrer, I.; Portero Otin, M. Article d'investigació
Subclinical atheromatosis localization and burden in a low-to-moderate cardiovascular risk population: the ILERVAS study 2021 Bermudez Lopez; M. Martinez Alonso; M. Castro Boque; E. Betriu; A. Cambray; S. Farras; C. Barbe; F. Pamplona; R. Lecube; A. Mauricio; D. Purroy; F. Valdivielso; J. M. Fernandez; E. Article d'investigació
Decrease in sleep depth is associated with higher cerebrospinal fluid neurofilament light levels in patients with Alzheimer's disease 2021 Targa, A.; Dakterzada, F.; Benítez, I.; López, R.; Pujol, M.; Dalmases, M.; Arias, A.; Sánchez de la Torre, M.; Zettenberg, H.; Blennow, K.; Pamplona, R.; Jové, M.; Barbé, F.; Piñol-Ripoll, G. Article d'investigació
Clinical Usefulness of Anthropometric Indices to Predict the Presence of Prediabetes. Data from the ILERVAS Cohort 2021 Sánchez, M.; Sánchez, E.; Bermúdez López, M.; Torres, G.; Farràs Sallés, C.; Pamplona, R.; Castro Boqué, E.; Valdivielso, J.M.; Purroy, F.; Martínez Alonso, M.; Godoy, P.; Mauricio, D.; Fernández, E.; Article d'investigació
Methionine transsulfuration pathway is upregulated in long-lived humans. 2021 Mota Martorell, N.; Jove, M.; Borras, C.; Berdun, R.; Obis, E.; Sol, J.; Cabre, R.; Pradas, I.; Galo Licona, J.D.; Puig, J.; Viña, J.; Pamplona, R. Article d'investigació
Prevalence of Obstructive Sleep Apnoea and Its Association With Atherosclerotic Plaques in a Cohort of Subjects With Mild-Moderate Cardiovascular Risk 2021 Sapiña-Beltrán E, Gracia-Lavedan E, Torres G, Gaeta AM, Paredes J, Mayoral A, Fernández E, Bermúdez-López M, Valdivielso JM, Farràs-Salles C, Pamplona R, Lecube A, de Batlle J, Barbé F, Dalmases M; IL Article d'investigació
Is the NDUFV2 subunit of the hydrophilic complex I domain a key determinant of animal longevity? 2021 Pamplona, R.; Jove, M.; Mota Martorell, N.; Barja, G. Article d'investigació
Obesity-associated deficits in inhibitory control are phenocopied to mice through gut microbiota changes in one-carbon and aromatic amino acids metabolic pathways. 2021 Arnoriaga Rodríguez, M.; Mayneris Perxachs, J.; Contreras Rodriguez, O.; Burokas, A.; Blasco, G.; Coll, C.; Biarnes, C.; Castells Nobau, A.; Puig, J.; Garre, J.; Ramos, R.; Pedraza, S.; Brugada, R.; V Article d'investigació
Age-Related Changes in Lipidome of Rat Frontal Cortex and Cerebellum Are Partially Reversed by Methionine Restriction Applied in Old Age 2021 Jové, M.; Cabré, R.; Mota Martorell, N.; Martin Garí, M.; Obis, È.; Ramos, P.; Canales, I.; Galo Licona, J.D.; Sol, J.; Nogueras, L.; Torres, P.; Portero Otín, M.; Ayala, V.; Ferrer, I.; Pamplona, R. Article d'investigació
Confirmation of the cardioprotective effect of MitoGamide in the diabetic heart. 2020 Park M; Nishimura T; Baeza-Garza CD; Caldwell ST; Boon Li Pun P; Prag HA; Young T; Sauchanka O; Logan A; Forkink M; Gruszczyk AV; Prime TA; Arndt S; Naudi A; Pamplona R; Coughlan MT; Tate M; Ritchie R Article d'investigació
Estrés oxidativo, envejecimiento y longevidad. 2020 Jove, M.; Pradas, I.; Pamplona, R.. Capítol de llibre docent
The advanced lipoxidation end-product malondialdehyde-lysine in aging and longevity. 2020 Jove, M.; Mota-Martorell, N.; Pradas, I.; Martin-Gari, M.; Ayala, V.; Pamplona, R. Review
Alterations in one-carbon metabolism in celiac disease. 2020 Martin-Masot, R.; Mota-Martorell, N.; Jove, M.; Maldonado, J.; Pamplona, R.; Nestares, T. Article d'investigació
Succination of protein thiols in human brain aging. 2020 Jove, M.; Pradas, I.; Mota-Martorell, N.; Cabre, R.; Ayala, V.; Ferrer, I.; Pamplona, R. Article d'investigació
Low abundance of NDUFV2 and NDUFS4 subunits of the hydrophilic complex I domain and VDAC1 predicts mammalian maximum longevity. 2020 Mota-Martorell, N.; Jove, M.; Pradas, I.; Sanchez, I.; Gomez, J.; Naudi, A.; Barja, G.; Pamplona, R. Article d'investigació
Protein succination as a potential surrogate biomarker of airway obstruction. The ilervas project. 2020 J. González; E. Gracia Lavedan; R. Pamplona; E. Fernández; A. Lecube; J. P. de Torres; F. Barbé; G. Torres; ILERVAS Study Group. Article d'investigació
Molecular phenomics of a high-calorie diet-induced porcine model of prepubertal obesity 2020 Jov,é M.; Tibau, J.; Serrano, JC.; Berdún, R.; Rodríguez Palmero, M.; Font-I-Furnols, M.; Cassanyé, A.; Rodriguez Mortera, R.; Sol, J.; Rassendren, H.; Fàbrega, E:; Crescenti, A.; Castell, A.; Sabater Article d'investigació
The Aging Imageomics Study: rationale, design and baseline characteristics of the study populatio 2020 Puig J, Biarnes C, Pedraza S, Vilanova JC, Pamplona R, Fernández-Real JM, Brugada R, Ramos R, Coll-de-Tuero G, Calvo-Perxas L, Serena J, Ramió-Torrentà L, Gich J, Gallart L, Portero-Otin M, Alberich-B Article d'investigació
Selected cryptic exons accumulate in hippocampal cell nuclei in Alzheimer's disease with and without associated TDP-43 proteinopathy 2020 Torres, P.; Andrés Benito, P.; Fernàndez Bernal, A.; Ricart, M.; Ayala, V.; Pamplona, R.; Ferrer, I.; Portero Otin, M. Article d'investigació
Metabolic adaptations in spontaneously immortalized PGC-1α knock-out mouse embryonic fibroblasts increase their oncogenic potential 2020 Prieto, I.; Alarcón, CR.; García-Gómez, R.; Berdún, R.; Urgel, T.; Portero, M.; Pamplona, R.; Martínez-Ruiz, A.; Ruiz-Sanz, JI.; Ruiz-Larrea, MB.; Jove, M.; Cerdán, S.; Monsalve, M. Article d'investigació
Gene expression and regulatory factors of the mechanistic target of rapamycin (mTOR) complex 1 predict mammalian longevity 2020 Mota Martorell, N.; Jove, M.; Pradas, I.; Berdún, R.; Sanchez, I.; Naudi, A.; Gari, E.; Barja, G.; Pamplona, R. Article d'investigació
Dietary intervention reverses fatty liver and altered gut microbiota during early-life undernutrition. 2020 Bauer, K.C.; Huus, K.E.; Brown, E.M.; Bozorgmehr, T.; Petersen, .CN.; Cirstea, M.S.; Woodward, S.E.; McCoy, J.; Hun, J.; Pamplona, R.; Ayala, V.; Finlay, B.B. Article d'investigació
Whole-Brain Dynamics in Aging: Disruptions in Functional Connectivity and the Role of the Rich Club 2020 Escrichs, A.; Biarnes, C.; Garre Olmo, J.; Fernandez Real, J.M.; Ramos, R.; Pamplona, R.; Brugada, R.; Serena, J.; Ramio Torrenta, L.; Coll de Tuero, G.; Gallart, L.; Barretina, J.; Vilanova, J.C.; Ma Article d'investigació
Lipid alterations in human frontal cortex in ALS-FTLD-TDP43 proteinopathy spectrum are partially related to peroxisome impairment 2020 Andres Benito, P.; Gelpi, E.; Jove, M.; Mota Martorell, N.; Obis, E.; Portero Otin, M.; Povedano, M.; Pujol, A.; Pamplona, R.; Ferrer, I. Article d'investigació
Gender-specific beneficial effects of docosahexaenoic acid dietary supplementation in G93A-SOD1 amyotrophic lateral sclerosis mice 2020 Torres P; Cacabelos D; Pairada J; Bauer KC; Boada J; Fontdevila L; Rossi C; Povedano M; Ferrer I; Pamplona R; Finlay BB; Portero-Otín M; Ayala V Article d'investigació
Are obesity indices useful for detecting subclinical atheromatosis in a middle-age population? 2020 Sánchez, E.; Sánchez, M., Betriu, À.; Rius, F.; Torres, G.; Purroy, F.; Pamplona, R.; Ortega, M.; López Cano, C.; Hernández, M.; Bueno, M.; Fernández, E.; Salvador, J.; Lecube, A. Article d'investigació
Lipidomic profiling identifies signatures of metabolic risk. 2020 Yin, X.; Willinger, C.M.; Keefe, J.; Liu, J.; Fernández Ortiz, A.; Ibáñez, B.; Peñalvo, J.; Adourian, A.; Chen, G.; Corella, D.; Pamplona, R.; Portero Otin, M.; Jove, M.; Courchesne, P.; van Duijn, C. Article d'investigació
Mediterranean diet, physical activity and subcutaneous advanced glycation end products accumulation: a cross-sectional analysis in The ILERVAS project 2020 Sánchez, E.; Betriu, À.; Salas Salvadó, J.; Pamplona, R.; Barbé, F.; Purroy, F.; Farràs, C.; Fernández, E.; López Cano, C.; Mizab, C.; Lecube, A. Article d'investigació
Obesity impairs short-term and working memory through gut microbial metabolism of aromatic amino acids. 2020 Arnoriaga-Rodríguez M; Mayneris-Perxachs J; Burokas A; Contreras-Rodríguez O; Blasco G; Coll C; Biarnés C; Miranda-Olivos R; Latorre J; Moreno-Navarrete JM; Castells-Nobau A; Sabater M; Palomo-Buitrag Article d'investigació
The lipidome fingerprint of longevity. 2020 Jove, M.; Mota-Martorell, N.; Pradas, I.; Galo-Licona, J.D.; Martin-Gari, M.; Obis, E.; Sol, J.; Pamplona, R. Review
Lipids and lipoxidation in human brain aging. Mitochondrial ATP-synthase as a key lipoxidation target. 2019 Jové, M; Pradas, I; Dominguez-Gonzalez, M; Ferrer, I; Pamplona, R. Article d'investigació
Redox lipidomics to better understand brain aging and function. 2019 Pamplona R; Borras C; Jove M; Pradas I; Ferrer I; Viña J. Article d'investigació
Dissimilar Impact of a Mediterranean Diet and Physical Activity on Anthropometric Indices: A Cross-Sectional Study from the ILERVAS Project 2019 Sánchez, M.; Sánchez, E.; Hernández, M.; Barril, S.; Purroy, F.; Rius, F.; Pamplona, R.; Farràs-Sallés, C.; Gutiérrez Carrasquilla, L.; Fernández, E.; Bermúdez-López, M.; Salvador, J.; Salas-Salvadó, Article d'investigació
Exceptional human longevity is associated with a specific plasma phenotype of ether lipids. 2019 Pradas, I.; Jové, M.; Huynh, K.; Puig, J.; Ingles, M.; Borras, C.; Viña, J.; Meikle, P.J.; Pamplona, R. Article d'investigació
Characteristics of atheromatosis in the prediabetes stage: a cross-sectional investigation of the Ilervas project. 2019 Sanchez, E.; Betriu, A.; Lopez Cano, C.; Fernandez, E.; Purroy, F.; Farras, C.; Barbe, F.; Pamplona, R.; Hernandez, C.; Simo, R.; Lecube, A. Article d'investigació
Subcutaneous advanced glycation end-products and lung function according to glucose abnormalities: The ILERVAS project. 2019 Sánchez, E.; Lecube, A.; Betriu, A.; Hernández, C.; López Cano, C.; Gutiérrez Carrasquilla, L.; Kerkeni, M.; Yeramian, A.; Purroy, F.; Pamplona, R.; Farràs, C.; Fernández, E.; Barbé, F.; Simó, R. Article d'investigació
Effects of aging and methionine restriction on rat kidney metabolome. 2019 Pradas I; Jove M; Cabre R; Ayala V; Mota-Martorell N; Pamplona R. Article d'investigació
Metformin induces lipid changes on sphingolipid species and oxidized lipids in polycystic ovary syndrome women. 2019 Pradas I; Rovira-Llopis S; Naudi A; Bañuls C; Rocha M; Hernandez-Mijares A; Pamplona R; Victor VM; Jove M. Article d'investigació
Manipulating mtDNA in vivo reprograms metabolism via novel response mechanisms. 2019 Bahhir D; Yalgin C; Ots L; Järvinen S; George J; Naudí A; Krama T; Krams I; Tamm M; Andjelković A; Dufour E; Gonzales de Cosar J; Gerards M; Parhiala M; Pamplona R; Jacobs HT; Jõers P. Article d'investigació
Lipid profile of cerebrospinal fluid in multiple sclerosis patients: a potential tool for diagnosis. 2019 Nogueras L; Gonzalo H; Jové M; Sol J; Gil-Sanchez A; Hervás JV; Valcheva P; Gonzalez-Mingot C; Solana MJ; Peralta S; Pamplona R; Brieva L. Article d'investigació
Deficient endoplasmic reticulum-mitochondrial phosphatidylserine transfer causes liver disease. 2019 Hernandez-Alvarez MI; Sebastian D; Vives S; Ivanova S; Bartoccioni P; Kakimoto P; Plana N; Veiga SR; Hernandez V; Vasconcelos N; Gopalacharyulu P; Adrover A; Jove M; Pamplona R; Berenguer-Llergo A; Go Article d'investigació
Biosynthesis de novo of glycerophospholipids and longevity. 2019 Mota-Martorell N; Pradas I; Jove M; Naudi A; Pamplona R. Article d'investigació
The cirrhotic liver is depleted of docosahexaenoic acid (DHA), a key modulator of NF-κB and TGFβ pathways in hepatic stellate cells. 2019 Enguita M; Razquin N; Pamplona R; Quiroga J; Prieto J; Fortes P. Article d'investigació
Essential physiological differences characterise short- and long-lived strains of Drosophila melanogaster 2019 Gubina N, Naudi A, Stefanatos R, Jove M, Scialo F, Fernandez-Ayala DJ, Rantapero T, Yurkevych I, Portero-Otin M, Nykter M, Lushchak O, Navas P, Pamplona R, Sanz A. Article d'investigació
Skin Autofluorescence Measurement in Subclinical Atheromatous Disease: Results from the ILERVAS Project. 2019 Sánchez, E.; Betriu, À.; Yeramian, A.; Fernández, E.; Purroy, F.; Sánchez de la Torre, M.; Pamplona, R.; Miquel, E.; Kerkeni, M.; Hernández, C.; Simó, R.; Lecube, A.; Hernández, M.; Rius, F.; Polanco, Article d'investigació
Effects of mediterranean diet and physical activity on pulmonary function: a cross-sectional analysis in the ILERVAS project. 2019 Gutiérrez Carrasquilla, L.; Sánchez, E.; Hernández, M.; Polanco, D.; Salas-Salvadó, J.; Betriu, À.; Gaeta, AM.; Carmona, P.; Purroy, F.; Pamplona, R.; Farràs, C.; López-Cano, C.; Fernández, E.; Lecube Article d'investigació
Biomarker identification, safety and efficacy of high-dose antioxidants for adrenomyeloneuropathy: a phase II pilot study. 2019 Casasnovas C; Ruiz M; Schlüter A; Naudi A; Fourcade S; Veciana M; Castañer S; Alberti A; Johnson M; Raymond G; Fatemi A; Moser AB; Villarroya F; Portero-Otin M; Artuch R; Pamplona R; Pujol A. Article d'investigació
Lung function measurements in the prediabetes stage: data from the ILERVAS Project 2019 Sánchez E.; Gutiérrez Carrasquilla, L.; Barbé F.; Betriu À, López Cano, C.; Gaeta AM.; Purroy F.; Pamplona R.; Ortega M.; Fernández E.; Hernández C.; Lecube A.; Simó R. Article d'investigació
A prospective pilot study using metabolomics discloses specific fatty acid, catecholamine and tryptophan metabolic pathways as possible predictors for a negative outcome after severe trauma 2019 Servià L.; Jové M.; Sol J.; Pamplona R.; Badia M.; Montserrat N.; Portero-Otin M.; Trujillano J. Article d'investigació
Impairment of mitochondrial redox status in peripheral lymphocytes of multiple sclerosis patients 2019 Gonzalo H; Nogueras L; Gil-Sánchez A; Hervás JV; Valcheva P; González-Mingot C; Martin-Gari M; Canudes M; Peralta S; Solana MJ; Pamplona R; Portero-Otin M; Boada J; Serrano JCE; Brieva L Article d'investigació
Aberrant regulation of the GSK-3 beta/NRF2 axis unveils a novel therapy for adrenoleukodystrophy 2018 Ranea-Robles P; Launay N; Ruiz M; Calingasan NY; Dumont M; Naudí A; Portero-Otín M; Pamplona R; Ferrer I; Beal MF; Fourcade S; Pujol A. Article d'investigació
Location-dependent effects of trauma on oxidative stress in humans 2018 Servia, L.; Serrano JCE.; Pamplona, R.; Badia, M.; Montserrat, N.; Portero-Otin, M.; Trujillano, J. Article d'investigació
Generation and quality control of lipidomics data for the alzheimer's disease neuroimaging initiative cohort. 2018 Barupal DK; Fan S; Wancewicz B; Cajka T; Sa M; Showalter MR; Baillie R; Tenenbaum JD; Louie G; Alzheimer's Disease Neuroimaging Initiative; Alzheimer's Disease Metabolomics Consortium; Kaddurah-Daouk Article d'investigació
Regional vulnerability to lipoxidative damage and inflammation in normal human brain aging 2018 Domínguez-González M, Puigpinós M, Jové M, Naudi A, Portero-Otín M, Pamplona R, Ferrer I. Article d'investigació
Lipidomics reveals altered biosynthetic pathways of glycerophospholipids and cell signaling as biomarkers of the polycystic ovary syndrome. 2018 Jové M; Pradas I; Naudí A; Rovira-Llopis S; Bañuls C; Rocha M; Portero-Otin M; Hernández-Mijares A; Victor VM; Pamplona R. Article d'investigació
Cryptic exon splicing function of TARDBP interacts with autophagy in nervous tissue. 2018 Torres, P.; Ramírez-Núñez, O.; Romero-Guevara, R.; Barés, G.; Granado-Serrano, A.B.; Ayala, V.; Boada, J.; Fontdevila, L.; Povedano, M.; Sanchís, D.; Pamplona, R.; Ferrer, I.; Portero-Otín, M. Article d'investigació
Lipid profile in human frontal cortex is sustained throughout healthy adult lifespan to decay at advanced ages 2018 Cabré R; Naudí A; Dominguez-Gonzalez M; Jové M; Ayala V; Mota-Martorell N; Pradas I; Nogueras L; Rué M; Portero-Otín M; Ferrer I; Pamplona R Article d'investigació
Lipidomics Reveals a Tissue-Specific Fingerprint 2018 Pradas I; Huynh K; Cabré R; Ayala V; Meikle PJ; Jové M; Pamplona R. Article d'investigació
Adipocyte lipopolysaccharide binding protein (LBP) is linked to a specific lipidomic signature. 2017 Moreno-Navarrete JM; Jove M; Padro T; Boada J; Ortega F; Ricart W; Pamplona R; Badimon L; Portero-Otin M; Fernandez-Real JM. Article d'investigació
A stress-resistant lipidomic signature confers extreme longevity to humans. 2017 Jové M; Naudí A; Gambini J; Borras C; Cabré R; Portero-Otin M; Viña J; Pamplona R Article d'investigació
Sixty years-old is the breakpoint of the human frontal cortex aging. 2017 Cabré R; Naudí A; Dominguez-Gonzalez M; Ayala V; Jové M; Mota-Martorell N; Piñol-Ripoll G;Gil-Villar MP; Rué M; Portero-Otín M; Ferrer I; Pamplona R Article d'investigació
Region-specific vulnerability to lipid peroxidation and evidence of neuronal mechanisms for polyunsaturated fatty acid biosynthesis in the healthy adult human central nervous system 2017 Naudí A, Cabré R, Dominguez-Gonzalez M, Ayala V, Jové M, Mota-Martorell N, Piñol-Ripoll G, Gil-Villar MP, Rué M, Portero-Otín M, Ferrer I, Pamplona R. Article d'investigació
Membrane lipid unsaturation as physiological adaption to animal longevity. 2017 Naudí A, Jové M, Ayala V, Portero-Otin M, Barja G, Pamplona R. Capítol de llibre docent
Targeted metabolomics and medication classification data from participants in the ADNI1 cohort. 2017 St John-Williams L; Blach C; Toledo JB; Rotroff DM; Kim S; Klavins K; Baillie R; Han X; Mahmoudiandehkordi S; Jack J; Massaro TJ; Lucas JE; Louie G; Motsinger-Reif AA; Risacher SL; Alzheimer's Disease Article d'investigació
Specific metabolomics adaptations define a differential regional vulnerability in the human cerebral cortex. 2017 Cabré R; Jové M; Naudí A; Ayala V; Piñol-Ripoll G; Gil-Villar MP; Dominguez-Gonzalez M; Obis E; Berdun R; Mota-Martorell N; Portero-Otin M; Ferrer I: Pamplona R. Capítol de llibre docent
A plasma metabolomic signature discloses human breast cancer. 2017 Jové M; Collado R; Quiles JL; Ramírez-Tortosa MC; Sol J; Ruiz-Sanjuan M; Fernandez M; De la Torre-Cabrera C; Ramirez-Tortosa C; Granados-Principal S; Sanchez-Rovira P; Pamplona R. Article d'investigació
Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance. 2017 Fourcade S; Morato L; Parameswaran J; Ruiz M; Ruiz-Cortes T; Jove M; Naudí A; Martinez-Redondo P; Dierssen M; Ferrer I; Villarroya F; Pamplona R; Vaquero A; Portero-Otin M; Pujol A. Article d'investigació
Tumour-microenvironmental blood flow determines a metabolomic signature identifying lysophospholipids and resolvin D as biomarkers in endometrial cancer patients. 2017 Eritja N; Jove M; Eldevik Fasmer K; Gatius S; Portero-Otin M; Trovik J; Krakstad C; Sol J; Pamplona R; Haldorsen IS; Matias-Guiu X. Article d'investigació
Differential metabolic profiles associated to movement behaviour of stream-resident brown trout (Salmo trutta) 2017 Oromi N; , Jové M; Pascual-Pons M; Royo JL; Rocaspana R; Aparicio E; Pamplona R; Palau A; Sanuy D; Fibla J, Portero-Otin M Article d'investigació
Nontargeted brain lipidomic profiling performed by UPLC-ESI-qTOF-MS/MS. 2017 Naudi A; Cabré R; Jové M; Pamplona R. Capítol de llibre docent
Early and gender-specific differences in spinal cord mitochondrial function and oxidative stress markers in a mouse model of ALS 2016 Cacabelos D; Ramírez-Núñez O; Granado-Serrano AB; Torres P; Ayala V; Moiseeva V; Povedano M; Ferrer I; Pamplona R; Portero-Otin M; Boada J. Article d'investigació
Oral intake of genetically engineered high-carotenoid corn ameliorates hepatomegaly and hepatic steatosis in PTEN haploinsufficient mice. 2016 Eritja N; Arjo G; Santacana M; Gatius S; Arcal L; Serrano JC; Pamplona R; Dolcet X; Piñol C; Christou P; Matias-Guiu X; Portero-Otin M. Article d'investigació
Metabolomics uncovers the role of adipose tissue PDXK in adipogenesis and systemic insulin sensitivity 2016 Moreno-Navarrete JM, Jove M, Ortega F, Xifra G, Ricart W, Obis E, Pamplona R, Portero Otin M, Fernández-Real JM. Article d'investigació
Redox proteomic profiling of neuroketal-adducted proteins in human brain: regional vulnerability at middle age increases in the elderly. 2016 Dominguez M; De Oliveira E; Odena MA; Portero M; Pamplona R; Ferrer I. Article d'investigació
Human Aging Is a Metabolome-related Matter of Gender 2016 Jové M, Maté I, Naudí A, Mota-Martorell N, Portero-Otín M, De la Fuente M, Pamplona R. Article d'investigació
Rapamycin reverses age-related increases in mitochondrial ROS production at complex I, oxidative stress, accumulation of mtDNA fragments inside nuclear DNA, and lipofuscin level, and increases autopha 2016 Martínez-Cisuelo V, Gómez J, García-Junceda I, Naudí A, Cabré R, Mota-Martorell N, López-Torres M, González-Sánchez M, Pamplona R, Barja G. Article d'investigació
Specific metabolomics adaptations define a differential regional vulnerability in the adult human cerebral cortex 2016 Cabré R; Jové M; Naudí A; Ayala V; Piñol-Ripoll G; Gil-Villar MP; Dominguez-Gonzalez M; Obis E; Berdun R; Mota-Martorell N; Portero-Otin M; Ferrer I; Pamplona R. Article d'investigació
Interplay between TDP-43 and docosahexaenoic acid-related processes in amyotrophic lateral sclerosis 2016 Cacabelos D; Ayala V; Granado-Serrano AB; Jové M; Torres P; Boada J; Cabré R; Ramírez-Núñez O; Gonzalo H; Soler-Cantero A; Serrano JC; Bellmunt MJ, Romero MP; Motilva MJ; Nonaka T; Hasegawa M; Ferrer Article d'investigació
Metabotyping human endometrioid endometrial adenocarcinoma reveals an implication of endocannabinoid metabolism 2016 Jove M; Gatius S; Yeramian A; Portero-Otin M; Eritja N; Santacana M; Ruiz M; Pamplona R; Matias-Guiu X. Article d'investigació
Metabolomics Predicts Neuroimaging Characteristics of Transient Ischemic Attack Patients 2016 Purroy F; Cambray S; Mauri-Capdevila G; Jove M; Sanahuja J; Farre J; Benabdelhak I; Molina-Seguin J; Colas-Campas L; Begue R; Gil MI; Pamplona R; Portero-Otin M. Article d'investigació
Activation of sirtuin 1 as therapy for the peroxisomal disease adrenoleukodystrophy 2015 Morató L, Ruiz M, Boada J, Calingasan NY, Galino J, Guilera C, Jové M, Naudí A, Ferrer I, Pamplona R, Serrano M, Portero-Otín M, Beal MF, Fourcade S, Pujol A. Article d'investigació
Metabolomics predicts stroke recurrence after transient ischemic attack 2015 Jové M, Mauri-Capdevila G, Suárez I, Cambray S, Sanahuja J, Quílez A, Farré J,Benabdelhak I, Pamplona R, Portero-Otín M, Purroy F. Article d'investigació
Voltage-gated calcium channel blockers deregulate macroautophagy in cardiomyocytes 2015 Pushparaj C, Das A, Purroy R, Nager M, Herreros J, Pamplona R, Cantí C. Article d'investigació
Obesity changes the human gut mycobiome 2015 Rodriguez MM, Chaves FJ, Perez D, Esteve E, Marin-Garcia P, Xifra G, Vendrell J, Jové M, Pamplona R, Ricart W, Portero-Otin M, Chacón MR, Fernández-Real JM. Article d'investigació
Altered glycolipid and glycerophospholipid signaling drive inflammatory cascades in adrenomyeloneuropathy 2015 Ruiz M, Jové M, Schlüter A, Casasnovas C, Villarroya F, Guilera C, Ortega FJ, Naudí A, Pamplona R, Gimeno-Martinez R, Fourcade S, Portero-Otín M, Pujol A. Article d'investigació
Neuroinflammatory Gene Regulation, Mitochondrial Function, Oxidative Stress, and Brain Lipid Modifications With Disease Progression in Tau P301S Transgenic Mice as a Model of Frontotemporal Lobar Dege 2015 López-González I, Aso E, Carmona M, Armand-Ugon M, Blanco R, Naudí A, Cabré R, Portero-Otin M, Pamplona R, Ferrer I. Article d'investigació
Lipidomics of Human Brain Aging and Alzheimer's Disease Pathology 2015 Naudí A, Cabré R, Jové M, Ayala V, Gonzalo H, Portero-Otín M, Ferrer I, Pamplona R. Review
Nutridynamics: mechanism(s) of action of bioactive compounds and their effects 2015 Serrano JC, Jove M, Gonzalo H, Pamplona R, Portero-Otin M. Article d'investigació
Cysteine dietary supplementation reverses the decrease in mitochondrial ROS production at complex I induced by methionine restriction 2015 Gomez A, Gomez J, Lopez Torres M, Naudí A, Mota-Martorell N, Pamplona R, Barja G. Article d'investigació
Target of rapamycin activation predicts lifespan in fruit flies 2015 Scialo F, Sriram A, Naudí A, Ayala V, Jové M, Pamplona R, Sanz A. Article d'investigació
Long lifespans have evolved with long and monounsaturated fatty acids in birds 2015 Galvan I, Naudi A, Erritzoe J, Moller AP, Barja G, Pamplona R. Article d'investigació
Neuroinflammatory signals in Alzheimer's disease and APP/PS1 transgenic mice: correlations with plaques, tangles, and oligomeric species 2015 Lopez-Gonzalez I, Schluter A, Aso E, Garcia-Esparcia P, Ansoleaga B, Llorens F, Carmona M, Moreno J, Fuso A, Portero-Otin M, Pamplona R, Pujol A, Ferrer I. Article d'investigació
Muscle mitohormesis promotes cellular survival via serine/glycine pathway flux 2015 Ost M, Keipert S, Van Schothorst EM, Donner V, Van der Stelt I, Kipp AP, Petzke KJ, Jove M, Pamplona R, Portero-Otin M, Keijer J, Klaus S. Article d'investigació
Deregulation of purine metabolism in Alzheimer's disease 2015 Ansoleaga B, Jove M, Schluter A, Garcia-Esparcia P, Moreno J, Pujol A, Pamplona R, Portero-Otin M, Ferrer I. Article d'investigació
The antioxidant effect of LMN diet, rich in polyphenols and polyunsaturated fatty acids, in Alzheimer’s disease. 2014 Fernandez-Fernandez L; Sole M; Bolea I; Valente T; Serrano JCE; Jove M; Ramirez B; Angles N; Reguant J; Morello JR; Pamplona R; Portero-Otin M; Unzeta M. Capítol de llibre docent
Caloric restriction reveals a lipidomic and metabolomic signature in liver of male mice. 2014 Jove M; Naudi A; Ramirez O; Portero-Otin M; Selman C; Withers DJ; Pamplona R. Article d'investigació
Estrés oxidativo, inflamación y envejecimiento. 2014 Naudi A; Portero-Otin M; Pamplona R. Capítol de llibre docent
Human omental and subcutaneous adipose tissue exhibit specific lipidomic signatures. 2014 Jove M; Moreno-Navarrete JM; Pamplona R; Ricart W; Portero-Otin M; Fernandez-Real JM. Article d'investigació
Metabolomics of human aging brain and age-related neurodegenerative diseases. 2014 Jove M; Portero-Otin M; Naudi A; Ferrer I; Pamplona R. Review
Plasma antioxidant capacity in critical polytraumatized patients?: methods, severity, and anatomic location 2014 Servia, L.; Trujillano, J.; Enrique Serrano, JCE.; Pamplona, R.; Badia, M.; Jove, M.; Justes, M.; Domingo, J.; Portero Otin, M. Article d'investigació
Dietary Lipid Unsaturation Influences Survival and Oxidative Modifications of an Amyotrophic Lateral Sclerosis Model in a Gender-Specific Manner 2014 Cacabelos D, Ayala V, Ramirez-Nuñez O, Granado-Serrano AB, Boada J, Serrano JCE, Cabre R, Nadal-Rey G, Bellmunt MJ, Ferrer I, Pamplona R, Portero-Otin M. Article d'investigació
Plasma lipidomics discloses metabolic syndrome with a specific HDL phenotype 2014 Jové M, Naudí A, Portero-Otin M, Cabré R, Rovira-Llopis S, Bañuls C, Rocha M, Hernández-Mijares A, Victor VM, Pamplona R. Article d'investigació
Independent and additive effects of atenolol and methionine restriction on lowering rat heart mitochondria oxidative stress 2014 Sanchez-Roman I, Gómez A, Naudí A, Jové M, Gomez J, Lopez-Torres M, Pamplona R, Barja G. Article d'investigació
Lifelong treatment with atenolol decreases membrane fatty acid unsaturation and oxidative stress in heart and skeletal muscle mitochondria and improves immunity and behaviour, without changing mice lo 2014 Gomez A, Sanchez-Roman I, Gomez J, Cruces J, Mate I, Lopez-Torres M, Naudi A, Portero-Otin M, Pamplona R, De la Fuente M, Barja G. Article d'investigació
Hydroxytyrosol ameliorates oxidative stress and mitochondrial dysfunction in doxorubicin-induced cardiotoxicity in rats with breast cancer. 2014 Granados-Principal S; El-Azem N; Pamplona R; Ramirez-Tortosa C; Pulido-Moran M; Vera-Ramirez L; Quiles JL; Sanchez-Rovira P; Naudi A; Portero-Otin M; Perez-Lopez P; Ramirez-Tortosa MC. Article d'investigació
Dietary intake of green tea polyphenols regulates insulin sensitivity with an increase in AMP-activated protein kinase content and changes in mitochondrial respiratory complexes 2013 Serrano JCE, Gonzalo-Benito H, Jové M, Fourcade S, Cassanyé A, Boada J, Delgado MA, Espinel AE, Pamplona R, Portero-Otín M. Article d'investigació
Atherosclerosis prevention by nutritional factors: a meta-analysis in small animal models. 2013 Jové M; Pamplona R; Prat J; Arola L and Portero-Otín M Article d'investigació
Exceptionally old mice are highly resistant to lipoxidation-derived molecular damage. 2013 Arranz L; Naudi A; De la Fuente M; Pamplona R. Article d'investigació
An evolutionary comparative view for longevity-related oxidative stress resistance mechanisms in animal species. 2013 Pamplona R; Barja G. Capítol de llibre docent
Estrés oxidativo, vulnerabilidad neuronal selectiva, y enfermedades neurodegenerativas asociadas a la edad. 2013 Naudi A; Jove M; Ayala V; Cacabelos D; Ramírez O; Ferrer I; Portero-Otin M; Pamplona R. Capítol de llibre docent
Vitamin D receptor BsmI polymorphism modulates soy intake and 25-hydroxyvitamin D supplementation benefits in cardiovascular disease risk factors profile. 2013 Serrano JCE; De Lorenzo D; Cassanye A; Martín-Gari M; Espinel A; Delgado MA; Pamplona R; Portero-Otin M. Article d'investigació
Estudio de la vulnerabilidad neuronal selectiva en el sistema nervioso central humano. 2013 Naudi A; Jove M; Ayala V; Cabre R; Portero-Otin M; Ferrer I; Pamplona R. Article d'investigació
Pioglitazone halts axonal degeneration in a mouse model of X-linked adrenoleukodystrophy. 2013 Morató L, Galino J, Ruiz M, Calingasan NY, Starkov AA, Dumont M, Naudi A, Martinez JJ, Aubourg P, Portero-Otín M, Pamplona R, Galea E, Beal MF, Ferrer I, Fourcade S, Pujol A. Article d'investigació
Skeletal muscle uncoupling-induced longevity in mice is linked to increased substrate metabolism and induction of the endogenous antioxidant defense system. 2013 Keipert S; Ost M; Chadt A; Voigt A; Ayala V; Portero-Otin M; Pamplona R; Al-Hasani H; Klaus S. Article d'investigació
Lipidomic and metabolomic analyses reveal potential plasma biomarkers of early atheromatous plaque formation in hamsters 2013 Jove M, Ayala V, Ramirez-Nuñez O, Serrano JCE, Cassanye A, Arola L, Caimari A, del Bas JM, Crescenti A, Pamplona R, Portero-Otin M. Article d'investigació
Tetratdecylthioacetic acid attenuates inflammation and has antioxidative potential during experimental colitis in rats. 2013 Bjorndal B; Grimstad TB; Cacabelos D; Nylund K; Aasprong OG; Omdal R; Portero-Otin M; Pamplona R; Lied GA; Hausken T; Berge RK. Article d'investigació
A salmon peptide diet alleviates experimental colitis as compared with fish oil 2013 Grimstad T, Bjørndal B, Cacabelos D, Aasprong O; Omdal R, Svardal A, Bohov P, Pamplona R, Portero-Otin M, Berge R, Hausken T. Article d'investigació
Formation of S-(Carboxymethyl)-cysteine in rat liver mitochondrial proteins. Effects of caloric and methionine restriction. 2013 Naudí A, Jové M, Cacabelos D, Ayala V, Cabré R, Caro P; Gómez J, Portero-Otín M, Barja G, Pamplona R Article d'investigació
Specific Lipidome Signatures in Central Nervous System from Methionine-Restricted Mice 2013 Jové M, Ayala V, Ramírez-Núñez O, Naudí A, Cabré R, Spickett CM, Portero-Otín M, Pamplona R. Article d'investigació
Impaired mitochondrial oxidative phosphorylation in the peroxisomal disease X-linked adrenoleukodystrophy 2013 López-Erauskin J, Galino J, Ruiz M, Cuezva JM, Fabregat I, Cacabelos D, Boada J, Martínez J, Ferrer I, Pamplona R, Villarroya F, Portero-Otín M, Fourcade S, Pujol A. Article d'investigació
Non-enzymatic modification of aminophospholipids by carbonyl-amine reactions 2013 Naudi A, Jove M, Ayala V, Cabre R, Portero-Otin M, Pamplona R. Review
Membrane lipid unsaturation as physiological adaptation to animal longevity 2013 Naudi A; Jove M; Ayala V; Portero-Otin M; Barja G; Pamplona R Article d'investigació
Long-life supplementation with atenolol converts the heart and skeletal muscle unsaturation of mitochondrial membranes of mice into those of ten fold longer-lived mammals. Effects on mean and maximum 2013 Gómez A; Naudí A; Pamplona R; Barja G. Article d'investigació
Plasma long-chain free fatty acids predict mammalian longevity 2013 Jove M, Naudi A, Aledo JC, Cabre R, Ayala V, Portero-Otin M, Barja G, Pamplona R. Article d'investigació
T-type calcium channel blockers inhibit autophagy and promote apoptosis of malignant melanoma cells 2013 Das A, Pushparaj C, Herreros J, Nager M, Vilella R, Portero M, Pamplona R, Matias-Guiu X, Martí RM, Cantí C. Article d'investigació
Lipidome analysis in multiple sclerosis reveals protein lipoxidative damage as a potential pathogenic mechanism. 2012 Gonzalo H; Brieva L; Tatzber F; Jové M; Cacabelos D; Cassanyé A; Lanau-Angulo L; Boada J; Serrano JC; González C; Hernández L; Peralta S; Pamplona R; Portero-Otin M. Article d'investigació
Amyloid generation and dysfunctional immunoproteasome activation with disease progression in animal model of familial Alzheimer's disease 2012 Aso E; Lomoio S; López-González I; Joda L; Carmona M; Fernández-Yagüe N; Moreno J; Juvés S; Pujol A; Pamplona R; Portero-Otin M; Martín V; Díaz M; Ferrer I. Article d'investigació
Region specific vulnerability to lipid peroxidation in the human central nervous system. 2012 Naudi A; Jove M; Ayala V; Ramirez O; Cabre R; Prat J; Portero-Otin M; Ferrer I; Pamplona R. Capítol de llibre docent
Dietary supplementation of krill oil attenuates inflammation and oxidative stress in experimental ulcerative colitis in rats. 2012 Grimstad T; Bjørndal B; Cacabelos D; Gunnar Aasprong O; Janssen EAM; Omdal R; Svardal A; Hausken T; Bohov P; Portero-Otin M; Pamplona R; Berge RK. Article d'investigació
Fish oil and 3-thia fatty acid have additive effects on lipid metabolism but antagonistic effects on oxidative damage when fed to rats for 50 weeks. 2012 Vigerust NAF; Cacabelos D; Burri L; Berge K; Wergedahl H; Christensen B; Portero-Otin M; Viste A; Pamplona R; Berge RK; Bjørndal B. Article d'investigació
Cellular dysfunction in diabetes as maladaptive response to mitochondrial oxidative stress 2012 Naudí A, Jové M, Ayala V, Cassanye A, Serrano J, Gonzalo H, Boada J, Prat J,Portero-Otín M,Pamplona R Review
Effects of aging and methionine restriction applied at old age on ROS generation and oxidative damage in rat liver mitochondria. 2012 Sanchez-Roman I; Gómez A; Sanchez C; Suarez H; Naudi A; Jove M; Lopez-Torres M; Pamplona R; Barja G. Article d'investigació
Functional expression of voltage-gated calcium channels in human melanoma 2012 Das A, Pushparaj C, Bahí N, Sorolla A, Herreros J, Pamplona R, Vilella R, Matias-Guiu X, Martí RM, Cantí C. Article d'investigació
DJ-1β regulates oxidative stress, insulin-like signaling and development in Drosophila melanogaster. 2012 Stefanatos R; Sriram A; Kiviranta E; Mohan A; Ayala V; Jacobs HT; Pamplona R; Sanz A. Article d'investigació
Plant-Derived Phenolics Inhibit the Accrual of Structurally Characterised Protein and Lipid Oxidative Modifications. 2012 Soler-Cantero A; Jové M; Cacabelos D.; Boada J.; Naudí A; Romero M.P.; Cassanyé A; Serrano J; Arola Ll; Valls J; Bellmunt MJ; Prat J; Pamplona R; Portero-Otín M; Motilva MJ Article d'investigació
Oxidative stress underlying axonal degeneration in adrenoleukodystrophy: A paradigm for multifactorial neurodegenerative diseases?. 2012 Galea E; Launay N; Portero-Otin M; Ruiz M; Pamplona R; Aubourg P; Ferrer I; Pujol A. Review
Membrane unsaturation, selective neuronal vulnerability, and age-related neurodegenerative diseases. 2011 Naudi A; Jove M; Cacabelos D; Ramirez O; Ayala V; Ilieva EV; Kichev A; Ferrer I; Portero-Otin M; Pamplona R. Capítol de llibre d'investigació
Prefrontal cortex, caloric restriction and stress during aging: studies on dopamine and acetylcholine release, BDNF and working memory. 2011 Del Arco A, Segovia G, De Blas M, Garrido P, Acuña-Castroviejo D, Pamplona R, Mora F. Article d'investigació
Antioxidants halt axonal degeneration in a mouse model of X-adenoleukodystrophy 2011 López-Erauskin J, Fourcade S, Galino J, Ruiz M, Schlüter A, Naudi A, Jove M, Portero-Otin M, Pamplona R, Ferrer I, Pujol A. Article d'investigació
Oxidative damage compromises energy metabolism in the axonal degeneration mouse model of X-adrenoleukodystrophy 2011 Galino J, Ruiz M, Fourcade S, Schlüter A, López-Erauskin J, Guilera C, Jove M, Naudi A, García-Arumí E, Andreu AL, Starkov AA, Pamplona R, Ferrer I, Portero-Otin M, Pujol A. Article d'investigació
Mitochondrial dysfunction and oxidative and endoplasmatic reticulum stress in argyrophilic grain disease 2011 Ilieva EV, Kichev A, Naudí A, Ferrer I, Pamplona R, Portero-Otín M. Article d'investigació
Age-related changes in brain mitochondrial DNA deletion and oxidative stress are differentially modulated by dietary fat type and coenzyme Q10 2011 Ochoa JJ, Pamplona R, Ramirez-Tortosa MC, Granados-Principal S, Perez-Lopez P, Naudí A, Portero-Otin M, López-Frías M, Battino M, Quiles JL. Article d'investigació
Stanozolol treatment decreases the mitochondrial ROS generation and oxidative stress induced by acute exercice in rat skeletal muscle 2011 Saborido A, Naudí A, Portero-Otín M, Pamplona R, Megías A. Article d'investigació
Resistencia a la insulina: ¿factor de riesgo o adaptación fisiológica?. 2011 Pamplona R; Serrano J; Boada J; Ayala V; Bellmunt MJ; Espinel A; Delgado MA; Portero-Otin M. Capítol de llibre docent
Nutrigenómica y nutrigenética. Hacia la dieta personalizada. 2011 De Lorenzo D; Serrano J; Portero-Otin M; Pamplona R. Editor llibre docent
Multicompartmental LC-Q-TOF-Based Metabonomics as an exploratory tool to identify novel pathways affected by polyphenol-rich diets in mice. 2011 Jove, M; Serrano, JCE; Ortega, N; Ayala, V; Angles, N; Reguant, J ; Morello, JR; Romero, MP ; Motilva, MJ; Prat, J ; Pamplona, R ; Portero-Otin, M Article d'investigació
Molecular and structural antioxidant defences against oxidative stress in animals. 2011 Pamplona R; Costantini D. Review
An evolutionary comparative scan for longevity-related oxidative stress resistance mechanisms in homeotherms. 2011 Pamplona R; Barja G. Article d'investigació
Forty percent methionine restriction lowers DNA methylation, complex I ROS generation, and oxidative damage to mtDNA and mitochondrial proteins in rat heart. 2011 Sanchez-Roman I; Gomez A; Gomez J; Suarez H; Sanchez C; Naudi A; Ayala V; Portero-Otin M; Lopez-Torres M; Pamplona R; Barja G. Article d'investigació
Mitochondrial DNA damage and animal longevity: Insights from comparative studies 2011 Pamplona R. Article d'investigació
Advanced Lipoxidation End-Products. 2011 Pamplona R. Review
Mitochondria and aging 2011 Sanz A; Pamplona R; Leeuwenburgh C. Review
Regultation of membrane unsaturation as antioxidant adaptative mechanism in long-lived animal species 2011 Naudí A, Jové M, Ayala V, Portero-Otín M, Barja G, Pamplona R. Article d'investigació
Cell stress induces TDP-43 pathological changes associated with ERK1/2 dysfunction: implications in ALS 2011 Ayala V, Granado-Serrano AB, Cacabelos D, Naudí A, Ilieva EV, Boada J, Caraballo-Miralles V, Lladó J, Ferrer I, Pamplona R, Portero-Otin M. Article d'investigació
Mitochondrial ATP-synthase in the entorhinal cortex is target of oxidative stress at stages I/II of Alzheimer's disease 2010 Terni B, Boada J, Portero-Otin M, Pamplona R, Ferrer I Article d'investigació
Endogenous toxins associated with life expectancy and aging 2010 Ayala V, Boada J, Serrano J, Portero-Otin M, Pamplona R Capítol de llibre docent
Longevity, Mitochondria and Oxygen free radicals 2010 Pamplona R, Barja G. Editor llibre docent
Oxidative stress resistance and longevity. 2010 Pamplona R, Barja G. Capítol de llibre docent
Estres oxidativo, envejecimiento y longevidad- 2010 Pamplona R. Capítol de llibre docent
Valproic acid induces antioxidant effects in X-adrenoleukodystrophy. 2010 Fourcade S, RUiz M, Guilera C, Hahnen E, Brichta L, Naudi A, Portero M, Dacremont G, Cartier N, Wanders R, Kemp S, Mandel JL, Wirth B, Pamplona R, Aubourg P, Pujol A. Article d'investigació
Depletion of oxidative and endoplasmic reticulum stress regulators in Pick disease. 2010 Ilieva EV, Naudi A, Kichev A, Ferrer I, Pamplona R, Portero-Otin M. Article d'investigació
Modification of brain lipids but not phenotype in alpha-synucleinopathy transgenic mice by long-term dietary n-3 fatty acids 2010 Muntane G, Janue A, Fernandez N, Odena MA, Oliveira E, Boluda S, Portero-Otin M, Naudi A, Boada J, Pamplona R, Ferrer I. Article d'investigació
Effects of Increased Iron Intake During the Neonatal Period on the Brain of Adult A beta PP/PS1 Transgenic Mice 2010 Fernandez L, Carmona M, Portero-Otin M, Naudi A, Pamplona R, Schroder N, Ferrer I. Article d'investigació
Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates. 2010 Martinez A, Portero-Otin M, Pamplona R, Ferrer I. Article d'investigació
Biomarkers of ageing in Drosophila 2010 Jacobson J, Lambert A, Portero-Otin M, Pamplona R, Magwere T, Miwa S, Driege Y, Brand MD, Partridge L. Article d'investigació
Mitochondrial DNA mutations induce mitochondrial dysfunction, apoptosis and sarcopenia in skeletal muscle of mitochondrial DNA mutator mice. 2010 Hiona A, Sanz A, Kujoth GC, Pamplona R, Seo AY, Hofer T, Someya S, Miyagawa T, Nakayama C, Samhan-Arias AK, Servais S, Barger JL, Portero-Otin M, Tanokura M, Prolla TA, Leeuwenburgh C. Article d'investigació
The beta-blocker atenolol lowers the longevity-related degree of fatty acid unsaturation, decreases protein oxidative damage and increases ERK signaling in heart of C57BL/6 mice. 2010 Sanchez-Roman I, Gomez J, Naudi A, Ayala V, Portero-Otin M, Lopez-Torres M, Pamplona R, Barja G. Article d'investigació
Dietary restriction and aging: a matter of calories? 2010 Pamplona R. Review
Pathological aspects of lipid peroxidation 2010 Negre-Salvayre A; Auge N; Ayala V; Basaga H; Boada J; Brenke R; Chapple S; Cohen G; Feher J; Grune T; Lengyel G; Mann GE; Pamplona R; Poli G; Portero-Otin M; Riahi Y; Salvayre R; Sasson S; Serrano J; Article d'investigació
Double-edged sword behaviour of gallic acid and its interaction with peroxidases in human microvascular endothelial cell culture (HMEC-1). Antioxidant and pro-oxidant effects 2010 Serrano J; Cipak A; Boada J; Gonzalo H; Cacabelos D; Cassanye A; Pamplona R; Zarkovic N; Portero-Otin M Article d'investigació
When cholesterol is not cholesterol: a note on the enzymatic determination of its concentration in model systems containing vegetable extracts 2010 Jové, M.; Serrano, J.C.; Bellmunt, M.J.; Cassanyé, A.; Anglès, N.; Reguant, J.; Morellá, J.R.; Pamplona, R.; Portero-Otín, M. Article d'investigació
Glycation of mitochondrial proteins, oxidative stress and aging 2010 Naudí A, Jové M, Ayala V, Portero-Otín M, Pamplona R Article d'investigació
Protein oxidative damage in diabetes 2010 Pamplona R; Ayala V; Boada J; Serrano J; Portero-Otin M. Capítol de llibre docent
Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction 2010 Sanz A; Soikkeli M; Portero-Otín M; Wilson A; Kemppainen E; McIlroy G; Ellilä S; Kemppainen KK; Tuomela T; Lakanmaa M; Kiviranta E; Stefanatos R; Dufour E; Hutz B; Naudí A; Jové M; Zeb A; Vartiainen S Article d'investigació
Coenzyme Q addition to and n6PUFA-rich diet partially resembles benefits on age-related mtDNA deletions and oxidative stress of a MUFA-rich diet in rat heart 2010 Quiles JL, Pamplona R, Ramirez-Tortosa MC, Naudi A, Portero-Otin M, Araujo-Nepomuceno E, Lopez-Frias M, Battino M, Mataix J, Ochoa JJ Article d'investigació
How to write and evaluate a scientific article for Revista Española de Geriatria y Gerontologia 2009 Formiga F, Baztan JJ, Montorio I, Pamplona R, Rodriguez-Molinero A Article d'investigació
Caloric restriction and aging in humans 2009 Pamplona R Review
Effect of 40% restriction of dietary amino acids -except methionine- on mitochondria oxidative stress and biogenesis, AIF and SIRT1 in rat liver. 2009 Caro P, Gomez J, Sanchez I, Garcia R, López-Torres M, Naudí A, Portero M.,Pamplona R, Barja G. Article d'investigació
Hyperglycemia and glycation in diabetic complications 2009 Negre-Salvayre A, Salvayre R, Auge N, Pamplona R, Portero-Otin M Review
Effect of methionine dietary supplementation on mitochondrial oxygen radical generation and oxidative DNA damage in rat liver and heart 2009 Gomez J, Caro P, Sanchez I, Naudi A, Jove M, Portero-Otin M, Lopez-Torres M, Pamplona R, Barja G Article d'investigació
Cell death and learning impairment in mice caused by in vitro modified pro-NGF can be related to its increased oxidative modifications in Alzheimer's disease. 2009 Kichev A, Ilieva EV, Piñol-Ripoll G, Podlesniy P, Ferrer I, Portero-Otin M, Pamplona R, Espinet C Article d'investigació
Dietary antioxidants interfere with Amplex Red-coupled-fluorescence assays 2009 Serrano J, Jové M, Boada J, Bellmunt MJ, Pamplona R, Portero-Otín M Article d'investigació
Forty percent methionine restriction decreases mitochondrial oxygen radical production and leak at complex I during forward electron flow and lowers oxidative damage to proteins and mitochondrial DNA 2009 Caro P, Gomez J, Sanchez I, Naudi A, Ayala V, Lopez-Torres M, Pamplona R, Barja G. Article d'investigació
Oxidación de Macromoléculas, Envejecimiento y Longevidad 2009 Naudí A,Jové M,Ilieva E, Cacabelos D, Gonzalo H, Serrano J,Boada J, Ayala V, Portero-Otín M, Pamplona R. Capítol de llibre docent
Free radicals and mammalian aging 2009 Sanz A, Barja G, Pamplona R, Leeuwenburgh C Capítol de llibre docent
Restricción calórica, envejecimiento y longevidad 2009 Pamplona R, Barja G Capítol de llibre docent
Biogerontologia Medica 2009 Sastre J, Pamplona R, Ramon J Editor llibre docent
El mito de las dietas y farmacos milagrosos 2009 Pamplona R Capítol de llibre docent
Estrés Oxidativo y Lípidos: determinación del índice de peroxidabilidad de los lípidos de membrana y la lesión lipoxidativa a proteínas. 2009 Naudí A,Jové M, Cacabelos D,Ilieva E, Gonzalo H, Serrano J, Ayala V, Boada J, Portero-Otín M, Pamplona R. Capítol de llibre docent
Bases biológicas del proceso de envejecimiento y la longevidad 2009 Naudí A,Caro P, Barja G, Pamplona R Capítol de llibre docent
Human Life and Aging 2009 Pamplona R Review
Type-dependent oxidative damage in frontotemporal lobar degeneration; cortical astrocytes are targets of oxidative damage 2008 Martínez A, Carmona M, Portero-Otin M, Naudí A, Pamplona R, Ferrer I. Article d'investigació
Membrane phospholipids, lipoxidative stress and molecular integrity:a causal role in aging and longevity 2008 Pamplona R Review
Innovación educativa en la universidad: la enseñanza de la Fisiología en el grado de Medicina. 2008 Gallego-Fernández R(ed.), Palés JL, Escanero JF, Sánchez-Bar E y colaboradores. Llibre docent
Increased oxidation, glycoxidation and lipoxidation of brain proteins in prion disease. 2008 Pamplona R, Naudi A, Gavin R, Pastrana MA, SajnaniG, Ilieva E, del Rio JA, Portero-Otin M, Ferrer I, Requena JR Article d'investigació
Early oxidative damage underlying neurodegeneration in x-adrenoleukodystrophy 2008 Fourcade S, Lopez-Erauskin J, Galino J, Duval C, Naudi A, Jove M, Villarroya F, Ferrer I, Pamplona R, Portero-Otin M, Pujol A Article d'investigació
Effect of every other day feeding on mitochondrial free radical production and oxidative stress in mouse liver 2008 Caro P, Gomez J, Lopez-Torres M, Sanchez I, Naudi A, Portero-Otin M, Pamplona R, Barja G Article d'investigació
Forty percent and eighty percent methionine restriction decrease mitochondrial ROS generation and oxidative stress in rat liver 2008 Caro P, Gomez J, Lopez-Torres M, Sanchez I, Naudi A, Jove M, Pamplona R, Barja G Article d'investigació
Maillard reaction versus other nonenzymatic modifications in neurodegenerative processes 2008 Pamplona R, Ilieva E, Ayala V, Bellmunt MJ, Cacabelos D, Dalfo E, Ferrer I, Portero-Otin M Article d'investigació
Inhibition of the renin-angiotensin system decreases renal protein oxidative damage in diabetic rats 2008 Portero-Otin M, Pamplona R, Boada J, Jove M, Gonzalo H, Buleon M, Linz W, Schafer S, Tack I, Girolami JP Article d'investigació
Resistencia a la insulina: factores desencadenantes 2008 Pamplona R, Boada J, Jove M, Gonzalo H, Bellmunt MJ and Portero-Otín M Capítol de llibre docent
Life and death: metabolic rate, membrane composition and life span. 2007 Hulbert AJ, Pamplona R, Buffenstein R, Buttemer W Review
Methionine restriction decreases endogenous oxidative molecular damage and increases mitochondrial biogenesis and uncoupling protein 4 in rat brain 2007 Naudi A, Caro P, Jove M, Gomez J, Boada J, Ayala V, Portero-Otin M, Barja G, Pamplona R Article d'investigació
The biological basis of the aging process 2007 Naudi A, Jove M, Cacabelos D, Ilieva E, Boada J, Ayala V, Portero-Otin M, Pamplona R Review
Oxidative and endoplasmic reticulum stress interplay in sporadic amyotrophic lateral sclerosis 2007 Ilieva EV, Ayala V, Jove M, Dalfo E, Cacabelos D, Povedano M, Bellmunt MJ, Ferrer I, Pamplona R, Portero-Otin M. Article d'investigació
Effect of graded corticosterone treatment on aging-related markers of oxidative stress in rat liver mitochondria 2007 Caro P, Gomez J, Sanz A, Portero-Otin M, Pamplona R, Barja G Article d'investigació
Estrés oxidativo, envejecimeinto y longevidad 2007 Pamplona R Capítol de llibre docent
Methylglyoxal induces advanced glycation endproduct (AGEs) formation and dysfunction of PDGF receptor-beta. Implications for diabetic atherosclerosis 2007 Cantero AV, Portero-Otin M, Sanson M, Ayala V, Auge N, Elbaz M, Thiers JC, Pamplona R, Salvayre R, Negre-Salvayre A Article d'investigació
Effect of 8.5% and 25% caloric restriction on mitochondrial free radical production and oxidative stress in rat liver 2007 Gomez J, Caro P, Naudi A, Portero-Otin M, Pamplona R, Barja G Article d'investigació
Highly resistant macromolecular components and low rate of generation of endogenous damage: two key traits of longevity 2007 Pamplona R, Barja G Review
Dietary protein restriction decreases oxidative protein damage, peroxidizability index, and mitochondrial complex I content in rat liver 2007 Ayala V, Naudí A, Sanz A, Caro P, Portero-Otin M, Barja G, Pamplona R. Article d'investigació
Is the mitochondrial free radical theory of aging intact? 2006 Sanz A, Pamplona R, Barja G. Article d'investigació
Is endogenous oxidative protein damage envolved in the aging process? 2006 Portero-Otin M, Pamplona R. Capítol de llibre docent
Differential effect of experimental and cold-induced hyperthyoridism on factors inducing rat liver oxidative damage. 2006 Venditti P, Pamplona R, Ayala V, De Rosa R, Caldarone G, DiMeo S. Article d'investigació
Effect of experimental and cold exposure induced hyperthyoridism on H2O2 production and susceptibility to oxidative stress of rat liver mitochondria. 2006 Venditti P, Pamplona R, Portero-Otin M, De Rosa R, DiMeo S. Article d'investigació
Mitochondrial oxidative stress, aging and caloric restriction: the protein and methionine connection 2006 Pamplona R,Barja G. Article d'investigació
Methionine restriction decreases mitochondrial oxygen radical generation and leak and oxidative damage to mitochondrial DNA and proteins. 2006 Sanz A, Caro P, Ayala V, Portero-Otin M, Pamplona R and Barja G. Article d'investigació
Glial fibrillary acidic protein is a major target of glycoxidative and lipoxidative damage in Pick's disease 2006 Muntane G, Dalfo E, Martinez A, Rey MJ, Avila J, Perez M, Portero M, Pamplona R, Ayala V, Ferrer I. Article d'investigació
Flight activity, mortality rates, and lipoxidative damage in Drosophila. 2006 Magwere T, Pamplona R, Miwa S, Martinez-Diaz P, Portero-Otin M, Brand MD, Partridge L. Article d'investigació
Effects of fasting on oxidative stress in rat liver mitochondria 2006 Sorensen M, Sanz A, Gomez J, Pamplona R, Portero-Otin M, Gredilla R, Barja G. Article d'investigació
Lesion oxidativa de proteinas de higado y corazon de rata durante el proceso de envejecimiento. 2006 Ayala V, Vasileva E, Fernandez E, Modol MT, Bellmunt MJ, Prat J, Requena JR, Portero-Otin M, Pamplona R. Article d'investigació
Protein and lipid oxidative damage and complex I content are lower in the brain of budgerigar and canaries than in mice. Relation to aging rate. 2005 Pamplona R, Portero-Otin M, Sanz A, Ayala V, Vasileva E, Barja G. Article d'investigació
Evidence of oxidative stress in the neocortex in incidental Lewy body disease. 2005 Dalfo E, Portero-Otin M, Ayala MV, Martinez A, Pamplona R, Ferrer I. Article d'investigació
Protein methionine content and MDA-lysine adducts are inversely related to maximum life span in the heart of mammals 2005 Ruiz MC, Ayala V, Portero-Otin M, Requena JR, Barja G, Pamplona R. Article d'investigació
Proteins in human brain cortex are modified by oxidation, glycoxidation and lipoxidation: effects of Alzheimer's disease and identification of lipoxidation targets. 2005 Pamplona R, Dalfo E, Ayala MV, Bellmunt MJ, Prat J, Ferrer I, Portero-Otin M. Article d'investigació
Effect of insulin and growth hormone on rat heart and liver oxidative stress in control and caloric restricted animals 2005 Sanz A, Gredilla R, Pamplona R, Portero-Otin M, Vara E, Tresguerres J, Barja G Article d'investigació
Regulation of longevity by mitochondria: Role of free radical production and membrane unsaturation.A comparative approach. 2005 Barja G, Portero-Otin M, Pamplona R. Capítol de llibre docent
Protein nonenzymatic modifications and proteasome activity in skeletal muscle from the short-lived rat and long-lived pigeon. 2004 Portero-Otin M, Requena JR, Bellmunt MJ, Ayala V, Pamplona R. Article d'investigació
Effect of ageing and caloric restriction on specific markers of protein oxidative damage and membrane peroxidizability in rat liver mitochondria. 2004 Lambert AJ, Portero-Otin M, Pamplona R, Merry BJ. Article d'investigació
Modification of the longevity-related degree of fatty acid unsaturation modulates oxidative damage to proteins and mitochondrial DNA in liver and brain. 2004 Pamplona R, Portero-Otin M, Sanz A, Requena JR, Barja G. Article d'investigació
Cold-induced hyperthyroidism produces oxidative damage in rat tissues and increases susceptibility to oxidants. 2004 Venditti P, De Rosa R, Portero-Otin M, Pamplona R, DiMeo S. Article d'investigació
AGEs in urine: are some sugars-derived products better than others? 2004 Pamplona R, Portero-Otin M. Article d'investigació
A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling. 2003 Echtay KS, Esteves T, Pakay JL, Jekabsons MB, Portero-Otin M, Pamplona R, Vidal-Puig AJ, Cawthorne MA, Roebuck SJ, Brand MD. Article d'investigació
Protein modification by advanced Maillard adducts can be modulated by dietary polyunsaturated fatty acids. 2003 Portero-Otin M, Bellmunt MJ, Requena JR, Pamplona R. Article d'investigació
Chemical and immunological characterization of oxidative nonenzymatic protein modifications in dialysis fluids 2003 Ruiz MC, Portero-Otin M, Pamplona R, Requena JR, Prat J, Lafarga MA, Borras M, Bellmunt MJ. Article d'investigació
Aging rate, free radical production, and constitutive sensitivity to lipid peroxidation: insights from comparative studies. 2003 Pamplona R, Barja G. Capítol de llibre docent
Oxidative, glycoxidative and lipoxidative damage to rat heart mitochondrial proteins is lower after four months of caloric restriction than in age-matched control. 2002 Pamplona R, Portero-Otin M, Requena JR, Gredilla R, Barja G. Article d'investigació
Aging increases Nepsilon-(carboxymethyl)lysine and caloric restriction decreases Nepsilon-(carboxyethyl)lysine and Nepsilon-(malondialdehyde)lysine in rat heart mitochondrial proteins. 2002 Pamplona R, Portero-Otin M, Bellmunt MJ, Gredilla R, Barja G. Article d'investigació
Protein oxidative stress in dialysis patients. 2002 Doñate T, Herreros A, Martinez E, Martinez J, Andres E, Cabezas A, Ortiz A, De Prado A, Pou JM, Pamplona R, Portero-Otin M, Bellmunt MJ. Capítol de llibre d'investigació
Oxidative damage and phospholipid fatty acyl composition in skeletal muscle mitochondria from mice underexpresing or overexpressing uncoupling protein 3. 2002 Brand MD, Pamplona R, Portero-Otin M, Requena JR, Roebuck SJ, Buckingham JA, Clapham JC, Cadenas S. Article d'investigació
Advanced glycation end product precursors impair epidermal growth factor receptor signaling 2002 Portero-Otin M, Pamplona R, Bellmunt MJ, Ruiz MC, Prat J, Salvayre R, Negre-Salvayre A. Article d'investigació
Membrane fatty acid unsaturation, protection against oxidative stress, and maximum life span - A homeoviscous-longevity adaptation? 2002 Pamplona R, Barja G, Portero-Otin M. Review
Correlation of fatty acid unsaturation of the major liver mitochondrial phospholipid classes in mammals to their maximum life span potential. 2001 Portero-Otin M, Bellmunt MJ, Ruiz MC, Barja G, Pamplona R. Article d'investigació
Effect of the degree of fatty acid unsaturation of rat heart mitochondria on their rates of H2O2 production and lipid and protein oxidative damage. 2001 Herrero A, Portero-Otin M, Bellmunt MJ, Pamplona R, Barja G. Article d'investigació
Influence of hyper- and hypothyroidism on lipid peroxidation, unsaturation of phospholipids, glutathione system and oxidative damage to nuclear and mitochondrial DNA in mice skeletal muscle. 2001 Gredilla R, Lopez-Torres M, Portero-Otín M, Pamplona R, Barja G. Article d'investigació
Nonenzymatic modification of aminophospholipids by the Maillard reaction in vivo. 2000 Portero-Otin M, Bellmunt MJ, Ruiz MC, Pamplona R. Capítol de llibre docent
Low fatty acid unsaturation: a mechanism for lowered lipoperoxidative modification of tissue proteins in mammalian species with long life span. 2000 Pamplona R, Portero-Otín M, Riva D, Requena JR, Thorpe SR, López-Torres M, Barja G. Article d'investigació
Double bond content of phospholipids and lipid peroxidation negatively correlate with maximum longevity in the heart of mammals. 2000 Pamplona R, Portero-Otin M, Ruiz MC, Gredilla R, Herrero A, Barja G. Article d'investigació
Diabetes induces an impairment in the proteolytic activity against oxidized proteins and a heterogeneous effect in nonenzymatic protein modifications in the cytosol of rat liver and kidney. 1999 Portero Otín, M.; Pamplona R.; Ruiz MC.; Cabiscol E.; Prat J.; Bellmunt MJ. Article d'investigació
A low degree of fatty acid unsaturation leads to lower lipid peroxidation and lipoxidation derived protein modification in heart mitochondria of the longevous pigeon than in the short-lived rat. 1999 Pamplona R, Portero-Otin M, Requena JR, Thorpe SR, Herrero A, Barja G. Article d'investigació
Effects of thyroid status on lipid composition and peroxidation in the mice liver 1999 Guerrero A, Pamplona R, Portero M, Barja G, López-Torres M. Article d'investigació
Tyroid status modulates glycoxidative and lipoxidative modification of tissue proteins. 1999 Pamplona R, Portero M, Ruiz MC, Bellmunt MJ, Requena JR, Thorpe SR, Baynes JW, Romero M, López-Torres M, Barja G. Article d'investigació
Heart fatty acid unsaturation and lipid peroxidation, and aging rate, are lower in the canary and the parakeet than in the mouse 1999 Pamplona R, Portero M, Riba D, Ledo F, Gredilla R, Herrero A, Barja G. Article d'investigació
Azúcar, diabetes y envejecimiento. 1998 Pamplona R Editor llibre docent
Carboxymethylated phosphatidylethanolamine in mithocondrial membranes of mammals: evidence for intracellular lipid glycoxidation 1998 Pamplona R, Requena JR, Portero-Otin M, Prat J, Thorpe SR, Bellmunt MJ. Article d'investigació
Mitochondrial membrane peroxidizability index is inversely related to maximum life span in mammals 1998 Pamplona R, Portero-Otin M, Riba D, Ruiz MC, Prat J, Bellmunt MJ, Barja G. Article d'investigació
Urinary pyrraline as a biochemical marker of non-oxidative Maillard reactions in vivo 1997 Portero,M; Pamplona,R; Bellmunt,MJ; Bergua,M; Nagaraj,RH; Prat,J Article d'investigació
La membrana mitocondrial y la longevidad de los mamíferos. 1997 Pamplona R. Review
Glycaemic control and in vivo non-oxidative Maillard reaction: urinary excretion of pyrraline in diabetes patients 1997 Portero,M; Pamplona,R; Bellmunt,MJ; Bergua,M; Prat,J Article d'investigació
Low fatty acid unsaturation protects against lipid peroxidation in liver mitochondria from longevous species: the pigeon and human case. 1996 Pamplona R, Prat J, Lopez-Torres M, Perez-Campo R, Rojas C, Cadenas S, Barja G. Article d'investigació
Effect of dietary vitamin E on fatty acid profiles and non-enzymatic lipid peroxidation in the guinea pig liver. 1996 Barja G, Cadenas S, Rojas C, Perez-Campo R, Lopez-Torres M, Prat J, Pamplona R. Article d'investigació
Composición en ácidos grasos de los pescados en conserva más comunes en la dieta española. Dieta y lípidos marinos (y II). 1996 Portero M, Aragon M, Vilardell F, Pamplona R, Bellmunt MJ, Prat J. Article d'investigació
Age-related fluorescence in rat lung collagen. 1995 Bellmunt MJ, Portero M, Pamplona R, Muntaner M, Prat J. Article d'investigació
Evidence for Maillard reaction in rat lung collagen and its relationship with solubility and age. 1995 Bellmunt MJ, Portero M, Pamplona R, Cosso L, Odetti P, Prat J. Article d'investigació
Composición en ácidos grasos de los pescados más comunes de la dieta española. Dieta y lípidos marinos. 1995 Vilardell F, Portero M, Aragon M, Bellmunt MJ, Pamplona R, Prat J. Article d'investigació
Chromatographic evidence for Amadori product formation in rat liver aminophospholipids. 1995 Pamplona R, Bellmunt MJ, Portero M, Riba D, Prat J. Article d'investigació
Glicación no enzimática y diabetes. 1995 Pamplona R Llibre d'investigació
Dietary vitamin C decreases endogenous protein oxidative damage, malondialdehyde, and lipid peroxidation and maintains fatty acid unsaturation in the guinea pig liver. 1994 Barja G, Lpoez M, Perez-Campo R, Rojas C, Cadenas S, Prat J, Pamplona R. Article d'investigació
Factores de riesgo cardiovascular y alimentación en el Pallars Sobirà (Lleida). 1994 Bergua M, Moron P, Muñoz M, Marion G, Pamplona R, Prat J, Lloveras G. Article d'investigació
Glycation, antioxidants and vascular disease. 1994 Pamplona R, Portero M, Costa S, Bellmunt MJ, Prat J. Capítol de llibre d'investigació
Relationship between lipid peroxidation, fatty acid composition and ascorbic acid in the liver during carbohydrate and caloric restriction in mice. 1993 Rojas C, Cadenas S, Perez-Campo R, Lopez-Torres M, Pamplona R, Prat J, Barja G. Article d'investigació
Mechanisms of glycation in atherogenesis. 1993 Pamplona R, Bellmunt MJ, Portero M, Prat J. Review
Composició en àcids greixosos dels peixos més comuns de la dieta. 1991 Vilardell F, Portero M, Aragon M, Bellmunt MJ, Pamplona R, Prat J. Article d'investigació
Glicación de apolipoproteínas. Implicaciones sobre las complicaciones vasculares de la diabetes 1991 Prat J, Pamplona R, Sorribas A, Navarro X. Review
Hemoglobina glicada y lípidos plasmáticos en una población no diabética. 1989 Prat J, Sorribas A, Pamplona R, Viñallonga M. Article d'investigació
Correlation of plasma lipid fractions with colorimetrically-determined glycated hemoglobin in a non diabetic population 1989 Prat J, Pamplona R, Sorribas A, Martin S, Viñallonga M, Segura R. Article d'investigació